DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dar1 and sp5b

DIOPT Version :9

Sequence 1:	NP_001097493.1	Gene:	dar1 / 38436	FlyBaseID:	FBgn0263239	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_005172147.1	Gene:	sp5b / 799504	ZFINID:	ZDB-GENE-131231-1	Length:	291	Species:	Danio rerio

Alignment Length:	385	Identity:	98/385 - (25%)
Similarity:	134/385 - (34%)	Gaps:	122/385 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   378 HQQQQHLQHNNSSSSSPK------LATPGDNSGNTSSYQQQYASQLVSGSGGGYLNGSSSNSYGY 436
            |...|....:.:|||:|:      |....|.........|...|         |:..:|.|...:
Zfish     3 HDPLQAFLQDRTSSSTPESIKSSPLMLLEDTCNRIGRASQSMES---------YIPYASPNKLFH 58

  Fly   437 SWHSSQSFH---TKYQIHPPSAAASATASATATPTAQLGAQQQQQQQQQQQLQQLCPPAAPSTPS 498
            .|.|:.|.|   :.:.|.|.......|.....:|...|.                ||.:..||..
Zfish    59 PWRSTDSTHLSQSTFSIPPLHQDMPLTEHFDCSPLKMLP----------------CPSSCISTCV 107

  Fly   499 TSSSSISSSSASSASRHMFVPPLTPPSSDPGSPGSSMVAAAAAAAAQRRTTPPPPYQQGHVMGLI 563
            .:.:.:     ..|.||:....:...||            |..::|..:.|      :|.::|
Zfish   108 PTHTGL-----VHAQRHLARDDIQWWSS------------ANHSSAHFQLT------RGWILG-- 147

  Fly   564 NPPPTLQLLGGAATGSNNSCTTTLTTLTPASAIQQQQQQPQQQQVPQQQPPPTPRSSGGGRRGRH 628
                                                  ||:                       .
Zfish   148 --------------------------------------QPE-----------------------F 151

  Fly   629 SHHQPGTAAHIASLMSVRTVRYNRRNNPELEKRRIHH-CDFVGCSKVYTKSSHLKAHQRIHTGEK 692
            .|:|.....:..|..|.|.:..|.:.|.:...||..| |...||:|||.|:||||||.|.|.||:
Zfish   152 GHYQSQILLNSKSRQSRRCMCPNCQKNADTPGRRKQHACHIPGCAKVYGKTSHLKAHLRWHAGER 216

  Fly   693 PYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRHL-PKNK 751
            |:.|.|..|...|.|||||.||.|.|||.|.|.|..|.:.|.||||||.|:|.|| .||:
Zfish   217 PFICSWMFCGKSFTRSDELQRHLRTHTGEKRFTCPDCSKRFMRSDHLAKHLKTHLMRKNR 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	42/83 (51%)
		C2H2 Zn finger	671..688	CDD:275368	12/16 (75%)
		zf-H2C2_2	680..707	CDD:290200	14/26 (54%)
		C2H2 Zn finger	696..718	CDD:275368	12/21 (57%)
		zf-H2C2_2	710..735	CDD:290200	13/24 (54%)
		C2H2 Zn finger	726..746	CDD:275368	11/19 (58%)
sp5b	XP_005172147.1	C2H2 Zn finger	193..212	CDD:275368	13/18 (72%)
		C2H2 Zn finger	220..242	CDD:275368	12/21 (57%)
		zf-H2C2_2	234..257	CDD:290200	12/22 (55%)
		zf-C2H2	248..270	CDD:278523	12/21 (57%)
		C2H2 Zn finger	250..270	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I4393
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.050