DRSC/TRiP Functional Genomics Resources

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Protein Alignment dar1 and Sp5

DIOPT Version :9

Sequence 1:NP_001097493.1 Gene:dar1 / 38436 FlyBaseID:FBgn0263239 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_071880.1 Gene:Sp5 / 64406 MGIID:1927715 Length:398 Species:Mus musculus


Alignment Length:368 Identity:115/368 - (31%)
Similarity:143/368 - (38%) Gaps:94/368 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   428 GSSSNSYGYSWHSSQSFHTKYQIHPPSAAASATASATATPTAQLGAQQQQQQQQQQQLQQLCPPA 492
            ||.|..: :.|.:....|:...:.||..:...|...|....: .||..:         ..|.|||
Mouse    64 GSPSRLF-HPWTADMPAHSPGALPPPHPSLGLTPQKTHLQPS-FGAAHE---------LPLTPPA 117

  Fly   493 APSTPSTSSSSISSSSASSASRHMFVPPLTPPSSDPGSPGS---SMVAAAAAAA-----AQRRTT 549
            .||.|                 :.|.|....|||....|.|   :.|..||.||     :.....
Mouse   118 DPSYP-----------------YEFSPVKMLPSSMAALPASCAPAYVPYAAQAALPPGYSNLLPP 165

  Fly   550 PPPPYQQGHVMGLINPPPTLQLLGGAATGSNNSCTTTLTTLTPASAIQQQQQQPQQQQVPQQQ-- 612
            ||||          .||||.:.|..|....:          .|..:|.|....|....||...  
Mouse   166 PPPP----------PPPPTCRQLSPAPAPDD----------LPWWSIPQSGAGPGSSGVPGTSLS 210

  Fly   613 -----PPPTPR--SSGGGRRGRHSHHQPGTA----------AHIASLMSVR-----TVRYNRR-- 653
                 ||..||  :|........:..|.|..          :.||:|:..:     |.|..||  
Mouse   211 SACAGPPHAPRFPASAAAAAAAAAALQRGLVLGPSDFAQYQSQIAALLQTKAPLAATARRCRRCR 275

  Fly   654 --------NNPELE--KRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARS 708
                    ..||.|  |::.|.|...||.|||.|:||||||.|.||||:|:.|.|..|...|.||
Mouse   276 CPNCQAAGGAPEAEPGKKKQHVCHVPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKSFTRS 340

  Fly   709 DELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRHLPKNK 751
            |||.||.|.|||.|.|.|..|.:.|.||||||.|:|.|  :||
Mouse   341 DELQRHLRTHTGEKRFACPECGKRFMRSDHLAKHVKTH--QNK 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dar1NP_001097493.1 COG5048 641..>724 CDD:227381 45/99 (45%)
C2H2 Zn finger 671..688 CDD:275368 12/16 (75%)
zf-H2C2_2 680..707 CDD:290200 15/26 (58%)
C2H2 Zn finger 696..718 CDD:275368 12/21 (57%)
zf-H2C2_2 710..735 CDD:290200 13/24 (54%)
C2H2 Zn finger 726..746 CDD:275368 11/19 (58%)
Sp5NP_071880.1 SP1-4_N 31..>47 CDD:425404
SP5_N 106..297 CDD:412096 55/236 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 160..215 16/74 (22%)
9aaTAD. /evidence=ECO:0000250|UniProtKB:Q6BEB4 187..195 2/7 (29%)
C2H2 Zn finger 301..320 CDD:275368 13/18 (72%)
COG5048 <311..384 CDD:227381 43/73 (59%)
C2H2 Zn finger 328..350 CDD:275368 12/21 (57%)
zf-H2C2_2 342..365 CDD:404364 12/22 (55%)
C2H2 Zn finger 358..378 CDD:275368 11/19 (58%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6780
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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