DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dar1 and Klf6

DIOPT Version :9

Sequence 1:	NP_001097493.1	Gene:	dar1 / 38436	FlyBaseID:	FBgn0263239	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_113830.2	Gene:	Klf6 / 58954	RGDID:	62389	Length:	317	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	98/286 - (34%)
Similarity:	131/286 - (45%)	Gaps:	88/286 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   477 QQQQQQQQLQQLCPPAAPSTPSTS----------SSSISSSSASSASRHMFVPPLTPPSSDPGSP 531
            ::::::.:|:....|...|..|:.          :|.:||.|:.|:..   :.|.|..:|||
  Rat   105 RERKEESELKISSSPPEDSLISSGFNYNLETNSLNSDVSSESSDSSEE---LSPTTKFTSDP--- 163

  Fly   532 GSSMVAAAAAAAAQRRTTPPPPYQQGHVMGLINPPPTLQLLGGAATGSNNSCTTTLTTLTPASAI 596
                                                    :|.....|.|..::.::|...:..:
  Rat   164 ----------------------------------------IGEVLVNSGNLSSSVISTPPSSPEV 188

  Fly   597 QQQQQQ-----PQQQQVPQQQPPPTPRSSGGGRRGRHSHHQPGTAAHIASLMSVRTVRYNRRNNP 656
            .::..|     |...        |:|.....|..|:......|.|                  :|
  Rat   189 NRESSQLWGCGPGDL--------PSPGKVRSGTSGKSGDKGSGDA------------------SP 227

  Fly   657 ELEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGA 721
            : .:||:|.|.|.||.||||||||||||||.|||||||.|.|..||||||||||||||:||||||
  Rat   228 D-GRRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGA 291

  Fly   722 KPFKCIVCERSFARSDHLALHMKRHL 747
            |||||..|:|.|:|||||||||||||
  Rat   292 KPFKCSHCDRCFSRSDHLALHMKRHL 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	52/82 (63%)
		C2H2 Zn finger	671..688	CDD:275368	15/16 (94%)
		zf-H2C2_2	680..707	CDD:290200	21/26 (81%)
		C2H2 Zn finger	696..718	CDD:275368	17/21 (81%)
		zf-H2C2_2	710..735	CDD:290200	19/24 (79%)
		C2H2 Zn finger	726..746	CDD:275368	14/19 (74%)
Klf6	NP_113830.2	COG5048	211..>299	CDD:227381	60/106 (57%)
		zf-C2H2	234..258	CDD:278523	19/23 (83%)
		C2H2 Zn finger	239..258	CDD:275368	16/18 (89%)
		zf-H2C2_2	250..>266	CDD:290200	14/15 (93%)
		C2H2 Zn finger	266..288	CDD:275368	17/21 (81%)
		zf-H2C2_2	280..305	CDD:290200	19/24 (79%)
		C2H2 Zn finger	296..316	CDD:275368	14/19 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D416605at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020