DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dar1 and sp5

DIOPT Version :9

Sequence 1:	NP_001097493.1	Gene:	dar1 / 38436	FlyBaseID:	FBgn0263239	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_989092.1	Gene:	sp5 / 394696	XenbaseID:	XB-GENE-1217606	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	345	Identity:	107/345 - (31%)
Similarity:	132/345 - (38%)	Gaps:	101/345 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   451 HPPSAAASATASATATPTAQLGAQQQQQQQQQQQLQQLCPPAAPSTPSTSSSSISSSSASSASRH 515
            ||.:...||.:|....|...:|.                        |||.:.::|...||...|
Frog    70 HPWTNEISAHSSGGIQPHNGIGL------------------------STSKTQLASHIQSSFVTH 110

  Fly   516 MFVPPLTPPSSDPGSP--GSSM-----VAAAAAAAAQRRTTPPPPYQQGHVMGLINPPPTLQLLG 573
            ..  ||||| :||..|  .|.|     ..||.....|....|..||..        |.|....|.
Frog   111 EL--PLTPP-ADPSYPYDYSPMKMLPPPMAAFQTGCQSPYVPAVPYAP--------PAPITSALH 164

  Fly   574 GAATGSNNSCTTTLTTLTPASAIQQQQQQPQQ------QQVPQ---QQPPPTPRSSGGGRRGRHS 629
            |.....:|..                .|||:|      :.:|.   ||..|...:|    ...|.
Frog   165 GFVPSHSNLI----------------HQQPRQLSPNPAEDMPWWSIQQATPVAHAS----TIPHP 209

  Fly   630 HH------------------QPGTAAHIASLMSVRTVRYNRR---------NNP-ELEKRRIHHC 666
            ||                  |...||.:.:...:.|.|..||         :.| |..|::.|.|
Frog   210 HHRFPIQRSLVLGHSDFAQYQTQIAALLQTKSPLATARRCRRCRCPNCQTSSGPDEAGKKKQHIC 274

  Fly   667 DFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCER 731
            ...||.|||.|:||||||.|.|:||:|:.|.|..|...|.|||||.||.|.|||.|.|.|..|.:
Frog   275 HIPGCGKVYGKTSHLKAHLRWHSGERPFICNWLFCGKSFTRSDELQRHLRTHTGEKRFVCPECGK 339

  Fly   732 SFARSDHLALHMKRHLPKNK 751
            .|.||||||.|:|.|  :||
Frog   340 RFMRSDHLAKHVKTH--QNK 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	42/92 (46%)
		C2H2 Zn finger	671..688	CDD:275368	12/16 (75%)
		zf-H2C2_2	680..707	CDD:290200	14/26 (54%)
		C2H2 Zn finger	696..718	CDD:275368	12/21 (57%)
		zf-H2C2_2	710..735	CDD:290200	13/24 (54%)
		C2H2 Zn finger	726..746	CDD:275368	11/19 (58%)
sp5	NP_989092.1	C2H2 Zn finger	277..296	CDD:275368	13/18 (72%)
		zf-C2H2	302..326	CDD:333835	12/23 (52%)
		C2H2 Zn finger	304..326	CDD:275368	12/21 (57%)
		zf-H2C2_2	318..341	CDD:372612	12/22 (55%)
		zf-C2H2	332..354	CDD:333835	12/21 (57%)
		C2H2 Zn finger	334..354	CDD:275368	11/19 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6780
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940