DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dar1 and btd

DIOPT Version :9

Sequence 1:	NP_001097493.1	Gene:	dar1 / 38436	FlyBaseID:	FBgn0263239	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_511100.1	Gene:	btd / 31912	FlyBaseID:	FBgn0000233	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	155/497 - (31%)
Similarity:	198/497 - (39%)	Gaps:	143/497 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 EKQQRQQQH-QHQQQQQQQQ-----QQQQQH--------QQQHQQQYQQQHYQQHYQQQHLYQHH 355
            :.|.:|||| ||||..||||     ||.|.|        ||||.|...||..||..|||...|
  Fly    15 QHQAQQQQHAQHQQHAQQQQHHLHMQQAQHHLHLSHQQAQQQHMQHLTQQQQQQQQQQQQQQQ-- 77

  Fly   356 PSLALPGLPPAVDVVELQLQQQHQQQQHLQHNNSSSSSPKLATPGDNSGNTSSYQQQYASQLVSG 420
                           :.|.|||.|||||    :..|::..|:.|...||::            ||
  Fly    78 ---------------QQQQQQQPQQQQH----DFLSAAALLSAPPSLSGSS------------SG 111

  Fly   421 SGGGYLNGSSSNSYGYSWHSSQSFHTKYQIHPPSAAASATASATATPTAQLGAQQQQQQQQQQQL 485
            |..|     ||..||..       ..|.::..|.|:::.|||    |.:.:        |.....
  Fly   112 SSSG-----SSPLYGKP-------PMKLELPYPQASSTGTAS----PNSSI--------QSAPSS 152

  Fly   486 QQLCPPAAPSTPSTSSSSISSSSASSASRHMFVPPLT---------PPSSDPGSPGSSMVAAAAA 541
            ..:.|...|| |:.|.:|||:|.::..:  ...||.|         |.||.|.|..:|..|||||
  Fly   153 ASVSPSIFPS-PAQSFASISASPSTPTT--TLAPPTTAAAGALAGSPTSSSPSSSAASAAAAAAA 214

  Fly   542 AAAQRRTTPPPPYQQGHVMGLINPPPTLQLLGGAATGS-NNSCTTTLTTLTPASAIQQQQQQPQQ 605
            |||....                       ||.||..| .....|..:.|.||     :.|.|..
  Fly   215 AAAAAAD-----------------------LGAAAVASAAYGWNTAYSGLGPA-----RSQFPYA 251

  Fly   606 QQVPQQQPPPTPRSSGGGRRGRHSH----HQPGTAAHIASL-------------MSVRTVRYNRR 653
            |............||..   ...||    :||.::......             .|||....|..
  Fly   252 QYASDYYGNAVGMSSSA---AWFSHQERLYQPWSSQSYPGFNFDDIAFQTQLQRRSVRCTCPNCT 313

  Fly   654 N---------NPELEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSD 709
            |         .|:...|:.|.|...||.::|.|:||||.|.|.||||:|:.|.  .|..||:|||
  Fly   314 NEMSGLPPIVGPDERGRKQHICHIPGCERLYGKASHLKTHLRWHTGERPFLCL--TCGKRFSRSD 376

  Fly   710 ELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRHLPKNK 751
            ||.||.|.||..:|:.|.:|.:.|:|||||:.|.|.|....|
  Fly   377 ELQRHGRTHTNYRPYACPICSKKFSRSDHLSKHKKTHFKDKK 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	38/104 (37%)
		C2H2 Zn finger	671..688	CDD:275368	9/16 (56%)
		zf-H2C2_2	680..707	CDD:290200	14/26 (54%)
		C2H2 Zn finger	696..718	CDD:275368	12/21 (57%)
		zf-H2C2_2	710..735	CDD:290200	11/24 (46%)
		C2H2 Zn finger	726..746	CDD:275368	10/19 (53%)
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	10/18 (56%)
		zf-H2C2_2	349..374	CDD:290200	14/26 (54%)
		C2H2 Zn finger	365..385	CDD:275368	12/21 (57%)
		zf-H2C2_2	377..402	CDD:290200	11/24 (46%)
		zf-C2H2	391..413	CDD:278523	10/21 (48%)
		C2H2 Zn finger	393..413	CDD:275368	10/19 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455412
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I1951
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.990