DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dar1 and Klf2

DIOPT Version :9

Sequence 1:NP_001097493.1 Gene:dar1 / 38436 FlyBaseID:FBgn0263239 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_001007685.1 Gene:Klf2 / 306330 RGDID:1359220 Length:351 Species:Rattus norvegicus


Alignment Length:326 Identity:107/326 - (32%)
Similarity:135/326 - (41%) Gaps:78/326 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   471 LGAQQQQQQQQQQQLQQLCPPAAPSTPSTSSSSISSSSASSASRHMFVPPLTPPSSDPGSPGSSM 535
            |||:...:...|.      ||.|...|...:.....:.|:.....:..|.|..|.. |...|..:
  Rat    55 LGAENPPEPPPQP------PPPAFYYPEPGAPPPYGTPAAGLGTELLRPDLDAPQG-PALHGRFL 112

  Fly   536 VAAAAAAAAQRRTTPPPPYQQGH----VMGLINPPPTLQLLGGAATGSNNSCTTTLTTLTPASAI 596
            :|...     |.....||...|.    ..||...|..|:|.|  |.|:..:|........|..: 
  Rat   113 LAPPG-----RLVKAEPPEVDGGGYGCAAGLARGPRGLKLEG--ALGATGACMRGPAGRPPPPS- 169

  Fly   597 QQQQQQPQQQQVPQQQPPPTPRS----------SGGGRRGRHSHHQPGTAAHIA----------- 640
               ...|.....|.:.|.|.||:          |.||         ||.|.|..           
  Rat   170 ---DTPPLSPDGPPRLPAPGPRNPFPPPFGPGPSFGG---------PGPALHYGPPAPGAFGLFD 222

  Fly   641 ------------------------SLMSVRTVRYNRRNNPELEKRRIHHCDFVGCSKVYTKSSHL 681
                                    .|:..:..| .||:.|. ::...|.|.:..|.|.|||||||
  Rat   223 DAAAALGLAPPATRGLLTPPSSPLELLEAKPKR-GRRSWPR-KRAATHTCSYTNCGKTYTKSSHL 285

  Fly   682 KAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRH 746
            |||.|.|||||||.|.|..|.|:||||||||||||||||.:||:|.:|:|:|:||||||||||||
  Rat   286 KAHLRTHTGEKPYHCNWDGCGWKFARSDELTRHYRKHTGHRPFQCHLCDRAFSRSDHLALHMKRH 350

  Fly   747 L 747
            :
  Rat   351 M 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dar1NP_001097493.1 COG5048 641..>724 CDD:227381 47/82 (57%)
C2H2 Zn finger 671..688 CDD:275368 13/16 (81%)
zf-H2C2_2 680..707 CDD:290200 18/26 (69%)
C2H2 Zn finger 696..718 CDD:275368 16/21 (76%)
zf-H2C2_2 710..735 CDD:290200 17/24 (71%)
C2H2 Zn finger 726..746 CDD:275368 14/19 (74%)
Klf2NP_001007685.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 20..110 13/61 (21%)
9aaTAD. /evidence=ECO:0000250|UniProtKB:Q9Y5W3 42..50
Interaction with WWP1. /evidence=ECO:0000250 110..264 33/175 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 156..209 14/65 (22%)
COG5048 <266..346 CDD:227381 54/79 (68%)
zf-C2H2 268..292 CDD:278523 15/23 (65%)
C2H2 Zn finger 270..292 CDD:275368 14/21 (67%)
zf-H2C2_2 284..>306 CDD:290200 15/21 (71%)
C2H2 Zn finger 300..322 CDD:275368 16/21 (76%)
zf-H2C2_2 314..339 CDD:290200 17/24 (71%)
C2H2 Zn finger 330..350 CDD:275368 14/19 (74%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.010

Return to query results.
Submit another query.