DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dar1 and Zfp353

DIOPT Version :9

Sequence 1:	NP_001097493.1	Gene:	dar1 / 38436	FlyBaseID:	FBgn0263239	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	XP_233185.6	Gene:	Zfp353 / 298232	RGDID:	1310095	Length:	551	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	86/373 - (23%)
Similarity:	134/373 - (35%)	Gaps:	118/373 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 SSYQQQYASQL--------VSG-----------SGGGYLNGSSSNSYGYSWHSSQSFHTKYQIHP 452
            :.||..|..|:        |.|           ||...|:...::.|.|    .|......|:
  Rat   257 NGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRY----DQDLIVNLQV-- 315

  Fly   453 PSAAASATASATATPTAQLGAQQQQQQQQQQQLQQLCPPAAPSTPSTSSSSISSSSASSASRHMF 517
                           |:.:|.:.....|        .|.:...|.|..:...:||...:.:.|
  Rat   316 ---------------TSPIGGEPLHDSQ--------IPNSNFDTTSCGTKRTTSSEEDNLAWH-- 355

  Fly   518 VPPLTPPSSDPGSPGSSMVAAAAAAAAQRRTTPPPPYQQGH-------------VMGLINPPPTL 569
              |.|..||:            .....|.||:........|             |..|.|..|.:
  Rat   356 --PETSLSSE------------ETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYV 406

  Fly   570 QLLGGAATGSNNSCTTTLTTLTPASAIQQQQQQPQQQQVPQQQPPPTPRSSGGGRRGRHSHHQPG 634
                |.::.::||         |...||.|:..                |:.|..:|:|...:
  Rat   407 ----GESSDTSNS---------PLIQIQPQEIS----------------SASGLDQGQHPEIK-- 440

  Fly   635 TAAHIASLMSVRTVRYNRRNNPELEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWP 699
                    :.::|.......||...||  :.|.:.||.|.|.||.|||.|.:.|||.|||.|..|
  Rat   441 --------LDLKTQSPVSLKNPHNSKR--YCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKP 495

  Fly   700 ECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRHL 747
            .|:|:|.|..:|.||.:||:|.:|:.|.:|.::::|..:|..|::.|:
  Rat   496 GCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHI 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	34/82 (41%)
		C2H2 Zn finger	671..688	CDD:275368	9/16 (56%)
		zf-H2C2_2	680..707	CDD:290200	15/26 (58%)
		C2H2 Zn finger	696..718	CDD:275368	9/21 (43%)
		zf-H2C2_2	710..735	CDD:290200	9/24 (38%)
		C2H2 Zn finger	726..746	CDD:275368	5/19 (26%)
Zfp353	XP_233185.6	C2H2 Zn finger	462..484	CDD:275368	11/21 (52%)
		C2H2 Zn finger	492..514	CDD:275368	9/21 (43%)
		zf-H2C2_2	506..531	CDD:290200	9/24 (38%)
		C2H2 Zn finger	522..542	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344879
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940