Protein Alignment dar1 and klf-1

DIOPT Version :10

• Sequence 1: NP_001097493.1
• Gene: dar1 / 38436
• FlyBaseID: FBgn0263239
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_497632.1
• Gene: klf-1 / 175404
• WormBaseID: WBGene00018990
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 142/516 - (27%)
• Similarity: 193/516 - (37%)
• Gaps: 158/516 - (30%)

  Fly   356 PSLALPGLPP-AVDVVELQLQQQHQQQQHLQHNNSSSSSPK--------LATPGDN--------- 402
            |.:.:|..|. ::|.:....:..|......|...||.||..        .||...|
 Worm    14 PLIHIPNKPSLSIDPLARADRSVHLSPSFFQPGLSSISSENDDAEQRIHEATRSFNQFGHQFYES 78

  Fly   403 ----SGNTSSYQQQYASQL------VSGSGGGYLNGSSSNSY--------GYSWHSSQSFHTKYQ 449
                |.:||:|::..|:.|      ..|:..|....|||:|.        .::.:.:..|.:...
 Worm    79 IRELSESTSAYERLKANALRRKLENTFGNDSGAATSSSSSSVFERQSDFSAFAPYKNSHFDSTQS 143

  Fly   450 IHPPSAA------------------ASATASATATPTAQLGAQQQQQQQQQQ------------- 483
            :..|:.:                  :.::.|...|||..|||..|..|.::.
 Worm   144 LFQPTTSFNDRLEQIKSDFIAEHQKSMSSFSGFNTPTTALGAAFQGMQVKKSAFAPVLLRENLDT 208

  Fly   484 ------------------QLQQLCPPAAPSTP-----STSSSSISSSSASSASRHMFVPPLTPPS 525
                              |.:.|....|.:.|     |||:..|:||| |..|.|.....:....
 Worm   209 RRPGGHLISDILNRDPLPQSRNLNLNMARNVPIRLIHSTSNFDIASSS-SGDSGHQDHESIVVED 272

  Fly   526 SDPGSPGSSMVAAAAA------------AAAQRRTTPPPPYQQGHVMGLI--NPPPTL------Q 570
            :|..||.|..|..:|.            ..:...|:..|......|...:  |..|..      :
 Worm   273 ADMDSPTSPCVKRSAMNFDLRDEPLTVNVESVSSTSDLPSSVSSSVNSFVYQNFDPLEFKRKIDE 337

  Fly   571 LLGGAATG---SNNSCTTTLTTLTPASAIQQQQQQPQQQQVPQQQP------------PPTPRSS 620
            |...|...   ..|.....:...|...||::|.::.|.......|.            .|:|.||
 Worm   338 LTASACLAVMPDANGQVDPMAIKTQLDAIKKQMEEHQTHMAEASQRLHVDSSLEDSNCEPSPSSS 402

  Fly   621 GGGRRGRHSHHQPGTAAHIASLMSVRTVRYNRRNNPELEKRRIHHCDFVGCSKVYTKSSHLKAHQ 685
                             :.||..||               :|:|||....|.||||||||||||.
 Worm   403 -----------------YDASEPSV---------------KRLHHCTHPNCGKVYTKSSHLKAHF 435

  Fly   686 RIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRH 746
            |.|||||||.|.|..|:||||||||||||||||||.:||||..|.|:|:|||||:||||||
 Worm   436 RTHTGEKPYECSWDGCDWRFARSDELTRHYRKHTGDRPFKCSQCSRAFSRSDHLSLHMKRH 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	49/82 (60%)
		C2H2 Zn finger	671..688	CDD:275368	14/16 (88%)
		C2H2 Zn finger	696..718	CDD:275368	17/21 (81%)
		zf-H2C2_2	710..735	CDD:463886	18/24 (75%)
		C2H2 Zn finger	726..746	CDD:275368	13/19 (68%)
klf-1	NP_497632.1	C2H2 Zn finger	419..438	CDD:275368	14/18 (78%)
		zf-H2C2_2	430..457	CDD:463886	19/26 (73%)
		C2H2 Zn finger	446..468	CDD:275368	17/21 (81%)
		zf-H2C2_2	460..485	CDD:463886	18/24 (75%)
		C2H2 Zn finger	476..496	CDD:275368	13/19 (68%)