DRSC/TRiP Functional Genomics Resources

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Protein Alignment dar1 and KLF6

DIOPT Version :9

Sequence 1:NP_001097493.1 Gene:dar1 / 38436 FlyBaseID:FBgn0263239 Length:751 Species:Drosophila melanogaster
Sequence 2:NP_001291.3 Gene:KLF6 / 1316 HGNCID:2235 Length:283 Species:Homo sapiens


Alignment Length:283 Identity:102/283 - (36%)
Similarity:138/283 - (48%) Gaps:80/283 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   475 QQQQQQQQQQLQQLCPPAAPSTPS------TSS--SSISSSSASSASRHMFVPPLTPPSSDPGSP 531
            ::::::.:.::....|.....:||      |:|  |.:||.|:.|:..   :.|....:|||  .
Human    71 REKKEESELKISSSPPEDTLISPSFCYNLETNSLNSDVSSESSDSSEE---LSPTAKFTSDP--I 130

  Fly   532 GSSMVAAAAAAAAQRRTTPPPPYQQGHVMGLINPPPTLQLLGGAATGSNNSCTTTLTTLTPASAI 596
            |..:|::...:::...|.|..|                                           
Human   131 GEVLVSSGKLSSSVTSTPPSSP------------------------------------------- 152

  Fly   597 QQQQQQPQQQQ--VPQQQPPPTPRSSGGGRRGRHSHHQPGTAAHIASLMSVRTVRYNRRNNPELE 659
             :..::|.|..  ||.:.|.|....||       :..:||.             :.|...:|: .
Human   153 -ELSREPSQLWGCVPGELPSPGKVRSG-------TSGKPGD-------------KGNGDASPD-G 195

  Fly   660 KRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPF 724
            :||:|.|.|.||.||||||||||||||.|||||||.|.|..||||||||||||||:|||||||||
Human   196 RRRVHRCHFNGCRKVYTKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPF 260

  Fly   725 KCIVCERSFARSDHLALHMKRHL 747
            ||..|:|.|:|||||||||||||
Human   261 KCSHCDRCFSRSDHLALHMKRHL 283

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dar1NP_001097493.1 COG5048 641..>724 CDD:227381 53/82 (65%)
C2H2 Zn finger 671..688 CDD:275368 15/16 (94%)
zf-H2C2_2 680..707 CDD:290200 21/26 (81%)
C2H2 Zn finger 696..718 CDD:275368 17/21 (81%)
zf-H2C2_2 710..735 CDD:290200 19/24 (79%)
C2H2 Zn finger 726..746 CDD:275368 14/19 (74%)
KLF6NP_001291.3 9aaTAD, inactive. /evidence=ECO:0000269|PubMed:31375868 62..70
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 106..198 26/161 (16%)
COG5048 177..>265 CDD:227381 61/108 (56%)
C2H2 Zn finger 205..224 CDD:275368 16/18 (89%)
C2H2 Zn finger 232..254 CDD:275368 17/21 (81%)
zf-C2H2 260..282 CDD:333835 16/21 (76%)
C2H2 Zn finger 262..282 CDD:275368 14/19 (74%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D416605at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23235
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
33.020

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