DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dar1 and klf3

DIOPT Version :9

Sequence 1:	NP_001097493.1	Gene:	dar1 / 38436	FlyBaseID:	FBgn0263239	Length:	751	Species:	Drosophila melanogaster
Sequence 2:	NP_571934.3	Gene:	klf3 / 117603	ZFINID:	ZDB-GENE-011116-1	Length:	328	Species:	Danio rerio

Alignment Length:	345	Identity:	128/345 - (37%)
Similarity:	167/345 - (48%)	Gaps:	78/345 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   442 QSFHTKYQIHPPSAAASA-TASATATPTAQLG-AQQQQQQQQQQQLQQLCPPAAPSTPSTSSSSI 504
            :|..|...:.||:..:.| ...:...|:.||. :.:|.|...|.|::    |...|..:.||.|.
Zfish    21 KSHETFGMVLPPAVVSGAHLYPSHYHPSYQLPYSHRQSQDVHQAQIE----PVDLSIGNKSSGSS 81

  Fly   505 SSSSASSASRHMFVPPLTPPSS-DPGSPGSSMVAAAAAAAAQRR------TTPPPPYQQ------ 556
            .|||.:|:|     |..:|||. :..||        |:..:|.|      |.|.|...|
Zfish    82 PSSSLASSS-----PRASPPSPYEAHSP--------ASRCSQNRQLSPSLTLPIPAVTQVLTPFV 133

  Fly   557 ---GHVMGLINP-----PPTLQLLGGAATGSNNSCTTTLTTLTPA-----SAIQQQQQQPQQQQV 608
               |.:..:..|     ||:|.|       |.:...:.:|...||     |.|:.:......:.:
Zfish   134 SSPGMIPVIPMPLSVLYPPSLHL-------SPSIIISPVTPEDPANHKHFSVIKSENTSDHHELL 191

  Fly   609 PQQQPPPTPRSSGGGRRGRHSHHQPGTAAHIASLMSVRTV--RYNRRNNPE---------LEKRR 662
            ...:..|.|..:    :..||..:           ||.|.  .||.|.|.:         |:|||
Zfish   192 KPIKSEPHPEHT----QDNHSQEK-----------SVITALPNYNDRGNTQSPKVESPDLLKKRR 241

  Fly   663 IHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCI 727
            ||.|||.||:||||||||||||:|.|||||||.|.|..|.|:||||||||||||||||.|||.|.
Zfish   242 IHRCDFNGCNKVYTKSSHLKAHRRTHTGEKPYKCMWEGCTWKFARSDELTRHYRKHTGVKPFHCP 306

  Fly   728 VCERSFARSDHLALHMKRHL 747
            .|:|:|:||||||||.||||
Zfish   307 DCDRTFSRSDHLALHKKRHL 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	59/93 (63%)
		C2H2 Zn finger	671..688	CDD:275368	14/16 (88%)
		zf-H2C2_2	680..707	CDD:290200	18/26 (69%)
		C2H2 Zn finger	696..718	CDD:275368	16/21 (76%)
		zf-H2C2_2	710..735	CDD:290200	18/24 (75%)
		C2H2 Zn finger	726..746	CDD:275368	13/19 (68%)
klf3	NP_571934.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010