Protein Alignment dar1 and Klf4

DIOPT Version :10

• Sequence 1: NP_001097493.1
• Gene: dar1 / 38436
• FlyBaseID: FBgn0263239
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_446165.1
• Gene: Klf4 / 114505
• RGDID: 621445
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 680
• Identity: 166/680 - (24%)
• Similarity: 234/680 - (34%)
• Gaps: 267/680 - (39%)

  Fly   130 GESGASEAWPHLPAPSYASDVPHAQQQQLQPAGSPNSNSNGAYG---CAPLYDGAPYEVA----- 186
            |||..:.:...||:.|..:..|..:::.|:|||:|.:.......   ..|...|.||::|
  Rat     6 GESDMAVSDALLPSFSTFASGPAGREKTLRPAGAPTNRWREELSHMKRLPPLPGRPYDLAATVAT 70

  Fly   187 -LGYGGAVVASTGGATSSDKEYLYETKNKEALYADPLDDPYQRPVLWDDITTSIQNIDPENALML 250
             |..|||     |.|.||:...|...:.:|  :.|.||..:       .::.|:.:.:...|.:.
  Rat    71 DLESGGA-----GAACSSNNPALPRRETEE--FNDLLDLDF-------ILSNSLSHQESVAATVT 121

  Fly   251 SSSGSSNNNGSSNSSSNTGESATSQLPQVKMEAIDESLLETFSTPLLSPLEIKTEKQQRQQQHQH 315
            :|:.:|:::..::|...:..|..|                 ||.|:.:.
  Rat   122 TSASASSSSSPASSGPASAPSTCS-----------------FSYPIRAG---------------- 153

  Fly   316 QQQQQQQQQQQQQHQQQHQQQYQQQHYQQHYQQQHLYQHHPSLALPGLPPAVDVVELQLQQQHQQ 380
                                                                             
  Rat   154 ----------------------------------------------------------------- 153

  Fly   381 QQHLQHNNSSSSSPKLATPGDNSGNTSSYQQQYASQLVSGSGGGYLNGSSSNSYGYSWHSSQSFH 445
                            ..||..:|||               |||.|         ||..|:.
  Rat   154 ----------------GDPGVAAGNT---------------GGGLL---------YSRESAP--- 175

  Fly   446 TKYQIHPPSAAASATASATATPTAQLGAQQQQQQQQQQQL--QQLCPP-----------AAPSTP 497
                  ||:|..:.......:|:....|:..:.:.....:  ||..||           |:.|||
  Rat   176 ------PPTAPFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSTP 234

  Fly   498 S---TSSSSISSSSASSASRH-MFVPPLT--PPSSDPGSPGSSMVAAAAAAAAQRRTTPPPPYQQ 556
            .   ||.|.||.|..|....| :.|.|.:  ||...|.....::.:...:.:.:...:..|....
  Rat   235 GSEYTSPSVISVSKGSPDGSHPVVVAPYSGGPPRMCPKIKQEAVPSCTVSRSLEAHLSAGPQLSN 299

  Fly   557 GHVMGLINPPPTLQLLGGAATGSNNSCTTTLTTLTPASAIQQQQQQP------------------ 603
            ||.....:.|...||           .|.|..||:|...:..:...|
  Rat   300 GHRPNTHDFPLGRQL-----------PTRTTPTLSPEELLNSRDCHPGLPLPPGFHPHPGPSYPP 353

  Fly   604 -----QQQQVP-----QQQPP-------PTPRSSGGGRRGRHSHHQPGTAAHIASLMSVRTVRYN 651
                 .|.|||     :..||       |.|      :|||.|..:..||.|.
  Rat   354 FLPDQMQSQVPSLHYQELMPPGSCLPEEPKP------KRGRRSWPRKRTATHT------------ 400

  Fly   652 RRNNPELEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYR 716
                          ||:.||.|.||||||||||.|.|||||||.|.|..|.|:||||||||||||
  Rat   401 --------------CDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYR 451

  Fly   717 KHTGAKPFKCIVCERSFARSDHLALHMKRH 746
            ||||.:||:|..|:|:|:||||||||||||
  Rat   452 KHTGHRPFQCQKCDRAFSRSDHLALHMKRH 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	43/82 (52%)
		C2H2 Zn finger	671..688	CDD:275368	13/16 (81%)
		C2H2 Zn finger	696..718	CDD:275368	16/21 (76%)
		zf-H2C2_2	710..735	CDD:463886	17/24 (71%)
		C2H2 Zn finger	726..746	CDD:275368	14/19 (74%)
Klf4	NP_446165.1	KLF4_N	7..399	CDD:409228	103/569 (18%)
		COG5048	<394..477	CDD:227381	58/108 (54%)
		C2H2 Zn finger	401..423	CDD:275368	16/21 (76%)
		C2H2 Zn finger	431..453	CDD:275368	16/21 (76%)
		zf-H2C2_2	445..470	CDD:463886	17/24 (71%)
		C2H2 Zn finger	461..481	CDD:275368	14/19 (74%)