Protein Alignment dar1 and KLF18

DIOPT Version :9

• Sequence 1: NP_001097493.1
• Gene: dar1 / 38436
• FlyBaseID: FBgn0263239
• Length: 751
• Species: Drosophila melanogaster
• Sequence 2: NP_001345367.1
• Gene: KLF18 / 105378952
• HGNCID: 51793
• Length: 1052
• Species: Homo sapiens
• Alignment Length: 791
• Identity: 166/791 - (20%)
• Similarity: 255/791 - (32%)
• Gaps: 213/791 - (26%)

  Fly    53 AAANNNNNTSSNNNHSSNSSSNNSNGSQ--------TPNGNNN----SSLATGGHQHHQFHHHLH 105
            |.......||:.|.:........|.|:|        |..||.|    ..:.:.|:|
Human   372 ALCGGQMTTSTGNQNLYGGQMMTSTGNQTLYWGQMMTSTGNQNLCGEQVMTSTGNQ--------- 427

  Fly   106 HHHSHQHHHQHHHLHQHHSHSLQSGESGASEAWPHLPAPSYASDVPHAQQQQLQPAGSPNSNSNG 170
                                :|..|:...|....:|......:.   ...|.|....:..|.||.
Human   428 --------------------ALCGGQMTTSTGNQNLCGEQVMTS---TSNQTLCGEQTTTSTSNQ 469

  Fly   171 AYGCAPLYDGAPYEVALGYGGAVVASTGGATSSDKEYLYETKNKEALYADPLDDPYQRPVLWDDI 235
            .. |......:....|| |||.::.|||..|               ||             |..:
Human   470 TL-CGEQVTTSTGNQAL-YGGQMMTSTGNQT---------------LY-------------WGQM 504

  Fly   236 TTSIQNIDPENALMLSSSGSSNNNGS--SNSSSN---TGESATSQLPQVKMEAIDESLLETFSTP 295
            .||..|.:.....|.:|:|:....|.  :.|:||   .||..|:  |........|.:..:....
Human   505 MTSTGNQNLCGEQMTTSTGNQALYGGQMTTSTSNQTLCGEQMTT--PTSNQTLCGEQVTTSTGNQ 567

  Fly   296 LLSPLEIKTEKQQRQ---QQHQHQQQQQQQQQQQQQHQQQHQQQYQQQHYQQHYQQQHLYQHHPS 357
            .|...:|.|....:.   :|.......|....:|......:|..|..|
Human   568 ALYGGQITTSTSNQTLCGEQMTTSTSNQTLCGEQVTTSTGNQALYGGQ----------------- 615

  Fly   358 LALPGLPPAVDVVELQLQQQHQQQQHLQHNNSSSSSPKLATPGDNSGNTSSYQQQYASQLVSGSG 422
                             .......|.|.....::|:......|:....::|.|.....|:::.:|
Human   616 -----------------MMTSTGNQALYGGQMTTSASNQTLCGEQMTTSTSNQTLCEEQVMTSTG 663

  Fly   423 -----GGYLNGSSSNS--YGYSWHSSQSFHTKYQIHPPSAAASATAS----ATATPTAQLGAQQQ 476
                 |..:..|:.|.  ||....:|.|..|.......::.::.|..    .|:|....|...|.
Human   664 NQALCGEQMTTSTGNQALYGGQMTTSTSNQTLCGEQTTTSTSNQTLCGEQVTTSTGNQALYGGQM 728

  Fly   477 QQQQQQQQL-----------QQLCPPAAPSTPSTSSSSI--SSSSASSASRHMFVPPLTPPSSDP 528
            ......|.|           |.||  ....|.||.:.::  ...:.|::::.:....:|.|:|:.
Human   729 MTSTGNQTLYWGQMMTSTGNQNLC--GEQMTTSTGNQALYGGQMTTSTSNQTLCGEQMTTPTSNQ 791

  Fly   529 GSPGSSMVAAAAAAAAQRRTTPPPPYQQGHVMGLINPPPTLQLLGG----AATGSNNSCTTTLTT 589
            ...|..:..:....|..|              |.|....:.|.|.|    .:|.:...|...:||
Human   792 TLCGEQVTTSTGNQALYR--------------GQITTSTSNQTLCGEQMTTSTSNQTLCGEQVTT 842

  Fly   590 LTPASAI---QQQQQQPQQQQVPQQQPPPTPRSS-GGGRRGRHSHHQ------------------ 632
            .|...|:   |.......|.....|....|...: .||:...:|.:|
Human   843 STGNQALYGGQMMTSTGNQNLYGGQNMTSTDNQALYGGQMATYSGNQTLYGDQMLTLQVGNMTTL 907

  Fly   633 ---------------------PG----TAAHI--ASLMSVRTVRYNRRNNPELEKRRIHHCDFVG 670
                                 ||    :::|:  ..|...:|.......|||:.  |.:.|.:..
Human   908 TDDHSLYGGYMMSHQFSSLPYPGFLCFSSSHLIQGQLPKQKTQSCQFWKNPEVS--RPYVCTYED 970

  Fly   671 CSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFAR 735
            |...|:|:.||:.|.|.|||||||.|....|.|:|||||||.||.::|||.:|:.|.:|.::|||
Human   971 CKMSYSKACHLRTHMRKHTGEKPYVCDVEGCTWKFARSDELNRHKKRHTGERPYLCSICSKNFAR 1035

  Fly   736 SDHLALHMKRH 746
            ||||..|.|.|
Human  1036 SDHLKQHAKVH 1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	36/82 (44%)
		C2H2 Zn finger	671..688	CDD:275368	7/16 (44%)
		zf-H2C2_2	680..707	CDD:290200	15/26 (58%)
		C2H2 Zn finger	696..718	CDD:275368	12/21 (57%)
		zf-H2C2_2	710..735	CDD:290200	11/24 (46%)
		C2H2 Zn finger	726..746	CDD:275368	11/19 (58%)
KLF18	NP_001345367.1	C2H2 Zn finger	969..988	CDD:275368	7/18 (39%)
		zf-H2C2_2	980..1007	CDD:316026	15/26 (58%)
		C2H2 Zn finger	996..1018	CDD:275368	12/21 (57%)
		zf-H2C2_2	1010..1035	CDD:316026	11/24 (46%)
		C2H2 Zn finger	1026..1046	CDD:275368	11/19 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151397
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940