Protein Alignment CG10357 and PNLIP

DIOPT Version :10

• Sequence 1: NP_647821.2
• Gene: CG10357 / 38435
• FlyBaseID: FBgn0035453
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_000927.1
• Gene: PNLIP / 5406
• HGNCID: 9155
• Length: 465
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 89/317 - (28%)
• Similarity: 141/317 - (44%)
• Gaps: 47/317 - (14%)

  Fly    28 NQSTIYYLKPSADVSLENVEQLSSVESVKLIVHGYLGSCTHGSIMPL-RNAYTAQGYENVLVADW 91
            |::...:.:.:||.|..:.....:....:.|:||::.......:..: :|.:..:.. |.:..||
Human    60 NENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESV-NCICVDW 123

  Fly    92 GPVANLDYPSSRLAVKNVAQILAKLLEEFLQRHGISLEGVHVIGHSLGAHIAGRIGRYFNGSLGR 156
            ...:...|..:...::.|...:|..:|......|.|...|||||||||||.||..||..||::||
Human   124 KGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRTNGTIGR 188

  Fly   157 VTGLDPALPLFSSRSD-DSLHSNAAQFVDVIHTD-YPL-----FGDIRPRGTVDFYPNFGLAPQP 214
            :||||||.|.|....: ..|..:.|:|||||||| .|:     ||..:..|.:||:||.|: ..|
Human   189 ITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNGGV-EMP 252

  Fly   215 GCEN------VDVVAASKLLHEAYSCSHNRAVMFYAESIGMPENFPAVSC-SLTAIKSRRVEDCL 272
            ||:.      ||:....:...:..:|:|.|:..:|.:||..|:.|....| |.....:.:...|.
Human   253 GCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGFPCASYNVFTANKCFPCP 317

  Fly   273 ------------REKSKTNTENANDYQTVFMGEHVNRSATLYYYLETNGAPPYGQGR 317
                        |...|||.          :|:.        :||:|..|..:.:.|
Human   318 SGGCPQMGHYADRYPGKTND----------VGQK--------FYLDTGDASNFARWR 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10357	NP_647821.2	Pancreat_lipase_like	28..308	CDD:238363	86/306 (28%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:395099	88/311 (28%)
		PLAT_PL	355..465	CDD:238857	1/2 (50%)