Protein Alignment CG10357 and PLA1A

DIOPT Version :9

• Sequence 1: NP_647821.2
• Gene: CG10357 / 38435
• FlyBaseID: FBgn0035453
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_056984.1
• Gene: PLA1A / 51365
• HGNCID: 17661
• Length: 456
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 93/266 - (34%)
• Similarity: 126/266 - (47%)
• Gaps: 51/266 - (19%)

  Fly    28 NQSTIYYLKPSADVSLENVEQLSSVESVKLIVHGY--LG---SCTHGSIMPLRNAYTAQGYENVL 87
            |.|....::.|:|  |:| ...::....|||:||:  ||   |.....|..|..|..|    ||:
Human    60 NPSCGQLVEGSSD--LQN-SGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTLLRATNA----NVI 117

  Fly    88 VADWGPVANLDYPSSRL---AVKNVAQI-------LAKLLEEFLQRHGISLEGVHVIGHSLGAHI 142
            ..||      .|.|:.:   |||||.::       |.|||.     .|:|...:|:||.|||||:
Human   118 AVDW------IYGSTGVYFSAVKNVIKLSLEISLFLNKLLV-----LGVSESSIHIIGVSLGAHV 171

  Fly   143 AGRIGRYFNGSLGRVTGLDPALPLFSSRS-DDSLHSNAAQFVDVIHTDYPLFGDIRPRGTVDFYP 206
            .|.:|:.|.|.||::||||||.|.::..| ::.|.:..|.||:.||||....|...|.|.||::.
Human   172 GGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDNLGIRIPVGHVDYFV 236

  Fly   207 NFGLAPQPGCENVDVVAASKLLHEAYSCSHNRAVMFYAESIGMPEN------FPAVSCSLTAIKS 265
            |.| ..||||........|.|:     |.|.|||..|..::   ||      ||.  .|..|..:
Human   237 NGG-QDQPGCPTFFYAGYSYLI-----CDHMRAVHLYISAL---ENSCPLMAFPC--ASYKAFLA 290

  Fly   266 RRVEDC 271
            .|..||
Human   291 GRCLDC 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10357	NP_647821.2	Pancreat_lipase_like	28..308	CDD:238363	93/266 (35%)
PLA1A	NP_056984.1	Lipase	16..336	CDD:278576	93/266 (35%)
		Pancreat_lipase_like	49..332	CDD:238363	93/266 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910