DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10357 and lipca

DIOPT Version :9

Sequence 1:	NP_647821.2	Gene:	CG10357 / 38435	FlyBaseID:	FBgn0035453	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	287	Identity:	99/287 - (34%)
Similarity:	144/287 - (50%)	Gaps:	50/287 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LIVHGY-LGSCTHGSIMPLRNAY-TAQGYENVLVADWGPVANLDYP----SSRLAVKNVAQILAK 115
            :|:||: :.......|..|.:|. :::|..|||:|||..:|:..||    ::|:..:::|.:|:
Zfish    82 IIIHGWSVDGMMEKWISRLASALKSSEGNINVLIADWLTLAHQHYPIAAQNTRIVGQDIAHLLS- 145

  Fly   116 LLEEFLQRHGISLEGVHVIGHSLGAHIAGRIGRYFNGS--------LGRVTGLDPALPLFSSRS- 171
            .||:|.|   ..|..||:||:||||||:|     |.||        |||:||||||.|:|...|
Zfish   146 WLEDFKQ---FPLGKVHLIGYSLGAHISG-----FAGSNLAMSGRTLGRITGLDPAGPMFEGMSH 202

  Fly   172 DDSLHSNAAQFVDVIHTDYPL------FGDIRPRGTVDFYPNFGLAPQPGCE-NVDVVAASKLLH 229
            .|.|....|:|||.||| :.|      .|..:|....|||||.| :.||||: ::..:.|....|
Zfish   203 TDRLSPEDAKFVDAIHT-FTLQRMGLSVGIKQPVAHFDFYPNGG-SFQPGCQLHMQNIYAHLAQH 265

  Fly   230 ------EAYSCSHNRAVMFYAES-IGMPENFPAVSCS-LTAIKSRRVEDCLREKSKTNTENANDY 286
                  :...|:|.|||..:.:| :...:...|..|| .||.......||  .|::.|| ...|.
Zfish   266 GIMGFEQTVKCAHERAVHLFIDSLLNKDKQIMAYKCSDNTAFDKGNCLDC--RKNRCNT-LGYDI 327

  Fly   287 QTVFMGEHVNRSATLYYYLETNGAPPY 313
            :.|..|    :|..|  :|:|....||
Zfish   328 KKVRTG----KSKRL--FLKTRSHMPY 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10357	NP_647821.2	Pancreat_lipase_like	28..308	CDD:238363	96/280 (34%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	99/287 (34%)
		Pancreat_lipase_like	54..344	CDD:238363	97/281 (35%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910