| Sequence 1: | NP_647821.2 | Gene: | CG10357 / 38435 | FlyBaseID: | FBgn0035453 | Length: | 321 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_032535.2 | Gene: | Lpl / 16956 | MGIID: | 96820 | Length: | 474 | Species: | Mus musculus |
| Alignment Length: | 281 | Identity: | 91/281 - (32%) |
|---|---|---|---|
| Similarity: | 134/281 - (47%) | Gaps: | 43/281 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 57 LIVHGYLGSCTHGSIMP--LRNAYTAQGYENVLVADWGPVANLDYPSS----RLAVKNVAQILAK 115
Fly 116 LLEEFLQRHGISLEGVHVIGHSLGAHIAGRIGRYFNGSLGRVTGLDPALPLFS-SRSDDSLHSNA 179
Fly 180 AQFVDVIHT---DYP--LFGDIRPRGTVDFYPNFGLAPQPGC---ENVDVVAASKL--LHEAYSC 234
Fly 235 SHNRAVMFYAESIGMPEN-FPAVSC-SLTAIKSRRVEDCLREKSKTNTENANDYQTVFMGEHVN- 296
Fly 297 ----RSATLYYYLETNGAPPY 313 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG10357 | NP_647821.2 | Pancreat_lipase_like | 28..308 | CDD:238363 | 88/274 (32%) |
| Lpl | NP_032535.2 | Interaction with GPIHBP1. /evidence=ECO:0000250|UniProtKB:P06858 | 32..53 | ||
| lipo_lipase | 33..472 | CDD:132274 | 91/281 (32%) | ||
| Essential for determining substrate specificity. /evidence=ECO:0000250|UniProtKB:P06858 | 243..266 | 5/22 (23%) | |||
| Important for interaction with lipoprotein particles. /evidence=ECO:0000250|UniProtKB:P06858 | 417..421 | ||||
| Important for heparin binding. /evidence=ECO:0000250|UniProtKB:P06858 | 430..434 | ||||
| Interaction with GPIHBP1. /evidence=ECO:0000250|UniProtKB:P06858 | 443..467 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||