DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10357 and LOC100331214

DIOPT Version :9

Sequence 1:	NP_647821.2	Gene:	CG10357 / 38435	FlyBaseID:	FBgn0035453	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_002666287.3	Gene:	LOC100331214 / 100331214	-ID:	-	Length:	501	Species:	Danio rerio

Alignment Length:	360	Identity:	100/360 - (27%)
Similarity:	157/360 - (43%)	Gaps:	70/360 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ILCQFLGL--------HAALLD-SLLNQSTIYYLKPSADV----------SLEN----------- 45
            :||.||.|        .|||.: ::||....::|:...|:          ||.|
Zfish     6 LLCVFLWLVLNITGPFIAALEEGNVLNGVFDHFLEDLRDLSDVKKLNVKFSLRNPSQPDDDVCYI 70

  Fly    46 ----VEQLSS-----VESVKLIVHGYLGSCTHGSIMP--LRNAYTAQGYENVLVADWGPVANLDY 99
                .|.|||     .....|::||:..|....|.:.  :...|..:...||:|.||...|...|
Zfish    71 VRGKAETLSSCNFNHTSKTILVIHGWTVSGLFESWVEKLVAALYNREKDANVIVVDWLDTAQDHY 135

  Fly   100 PSSRLAVKNVAQILAKLLEEFLQRHGISLEGVHVIGHSLGAHIAGRIGRYFNGSLGRVTGLDPAL 164
            ..:....|.|.:.:...::...:...:.||.:|:||:|||||:||..|.:....:||:||||||.
Zfish   136 VVAAQNTKMVGREIGLFIDWIEETSNVPLENLHLIGYSLGAHVAGFAGSHTTNKIGRITGLDPAG 200

  Fly   165 PLFSS-RSDDSLHSNAAQFVDVIHTDYPLF---------GDIRPRGTVDFYPNFGLAPQPGCE-- 217
            |.|.. .:...|..:.|.||||:||    |         |..:|.|.||.|||.| :.||||.
Zfish   201 PDFEGVHAHGRLSPDDAHFVDVLHT----FTRGSLGLSIGIEQPVGHVDIYPNGG-SFQPGCNLR 260

  Fly   218 -NVDVVAASKL--LHEAYSCSHNRAVMFYAESIGMPENF-PAVSCSLTAIKSRRVEDCLREKSKT 278
             .::.:|:..:  ::.|..|.|.|::..:.:|:...|.. .|.||....:..|.|  ||  :.:.
Zfish   261 GALEKMASYGIFAINNAIRCEHERSIHLFIDSLLNEEAAGRAYSCGSNDMFDRGV--CL--QCRK 321

  Fly   279 NTENANDYQTVFMGEHVNRSATLYYYLETNGAPPY 313
            |..|...|..    ..|.::.::..:.:|.|:.|:
Zfish   322 NGCNTVGYDI----SKVRKARSVKMFTKTRGSMPF 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10357	NP_647821.2	Pancreat_lipase_like	28..308	CDD:238363	88/327 (27%)
LOC100331214	XP_002666287.3	lipo_lipase	47..487	CDD:132274	88/319 (28%)
		Pancreat_lipase_like	51..347	CDD:238363	85/308 (28%)
		PLAT_LPL	355..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910