Protein Alignment CG10359 and ANGPTL1

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001363692.1
• Gene: ANGPTL1 / 9068
• HGNCID: 489
• Length: 491
• Species: Homo sapiens
• Alignment Length: 453
• Identity: 127/453 - (28%)
• Similarity: 203/453 - (44%)
• Gaps: 85/453 - (18%)

  Fly    70 KELMT-----NLHDRVGILVTLDEDQRHRLEVIDKKLD---------QLVESSSARMESMKAQ-Q 119
            |:::|     ||.|.:       ..|:..::|:...:|         :|:...|..|.|...| .
Human    77 KDMITRMDLENLKDVL-------SRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLY 134

  Fly   120 LDFLHRL----DSFEHIQRLSRNTLDELKGETDQVFGPRNVRELKHKLRNRKKMKDISRTVRDVS 180
            :..||.:    |:...:.:|....|:.   .|:.:......|||:.|.          .::.|:.
Human   135 MQLLHEIIRKRDNSLELSQLENKILNV---TTEMLKMATRYRELEVKY----------ASLTDLV 186

  Fly   181 QEQYPSSGIGTFNESNLNLSSRLDALATLLASTALSVRSVQVEVANLSRAIRRQSRLIQGKGLRS 245
            ..|  |..|....|..|.:.||.|        |.:|...|||...::..:.:....|:.|..::.
Human   187 NNQ--SVMITLLEEQCLRIFSRQD--------THVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQR 241

  Fly   246 TPGQQPIFYGPSGL-NGPTATR-QLP----------SSCSYSFLSNHGILKV-QLTPESES--FY 295
            .||.......|..| ..||.:. ::|          ..|..:..:.|.:..: .:.||:.:  ..
Human   242 DPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQ 306

  Fly   296 VSCDED-----WTVILSRTSDDVNFERGWLDYRDGFGNLAGDFFIGLNKLHALTSSALHELRIVM 355
            :.|:..     ||||..||...|||.|.|.:|:.||||:.|::::||..::.|::...::|.|.:
Human   307 LWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIEL 371

  Fly   356 EDFSGNVAYAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAGDSLSYHAGAKFSTVDQDNDNCLEC 420
            ||:|....||.||.|.:..|.|.|.| .||.:|.|    ||||:.:|.|.:|:|:|:|.| ....
Human   372 EDWSDKKVYAEYSSFRLEPESEFYRL-RLGTYQGN----AGDSMMWHNGKQFTTLDRDKD-MYAG 430

  Fly   421 NCALRHKGAGWFNNCAKSNL------FGEYTTQNQPGETGIWWDTF-SGQNSLKRVRWMIRPI 476
            |||..|||..|:|.||.|||      .|.|.:::|   .||:|..: .|..||:.|:.||:||
Human   431 NCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQ---DGIFWAEYRGGSYSLRAVQMMIKPI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	80/233 (34%)
ANGPTL1	NP_001363692.1	PB1	74..138	CDD:383100	13/67 (19%)
		FReD	275..490	CDD:238040	79/223 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810