DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10359 and Angpt1

DIOPT Version :9

Sequence 1:	NP_001137882.1	Gene:	CG10359 / 38434	FlyBaseID:	FBgn0035452	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_006241671.1	Gene:	Angpt1 / 89807	RGDID:	628896	Length:	498	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	129/466 - (27%)
Similarity:	202/466 - (43%)	Gaps:	115/466 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RNLRNNQTRSRIPNNFRSIATPPIAPRCDYKELMTNLHDRVGILVTLDEDQRHRLEVIDKKLDQL 104
            :|...|.|.:.:     .|.|..::...:....:|::..:|       .:|..|||:      ||
  Rat   117 QNAVQNHTATML-----EIGTSLLSQTAEQTRKLTDVETQV-------LNQTSRLEI------QL 163

  Fly   105 VES--SSARMESMKAQQLDFLHRLDS----FEH----IQRLSRNTLDELKGETDQVFG--PRN-- 155
            :|:  |:.::|....||.:.:.::..    .||    ::...:..||.||.|.:.:.|  .|.
  Rat   164 LENSLSTYKLEKQLLQQTNEILKIQEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTF 228

  Fly   156 -VRELKHKLRNRKKMKDISRTVRDVSQEQYPSSGIGTFNESNLNLSSRLDALATLLASTALSVRS 219
             ::||:         |.:||..                |.:::....:|:.:.|
  Rat   229 IIQELE---------KQLSRAT----------------NNNSVLQKQQLELMDT----------- 257

  Fly   220 VQVEVANLSRAIRRQSRLIQG------KGLRSTPGQQPIFYGPSGLNGPTATRQLPSSCSYSFLS 278
                |.||.....::..|::|      |..|.........:..||:              |:...
  Rat   258 ----VHNLVSLCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGI--------------YTIYF 304

  Fly   279 NHGILKVQLTPESESFYVSCDED---WTVILSRTSDDVNFERGWLDYRDGFGNLAGDFFIGLNKL 340
            |:       .||.:..:.:.|.:   ||||..|....::|:|||.:|:.||||.:|::::|...:
  Rat   305 NN-------MPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFI 362

  Fly   341 HALTSSALHELRIVMEDFSGNVAYAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAG--DSLSYHA 403
            .|:||...:.|||.:.|:.||.||:.|..|.||:||:.|.|.|.|.     |.:||  .||..|
  Rat   363 FAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGH-----TGTAGKQSSLILH- 421

  Fly   404 GAKFSTVDQDNDNCLECNCALRHKGAGWFNNCAKSNLFGEYTT--QNQPGETGIWWDTFSGQN-S 465
            ||.|||.|.|||||: |.|||...|..||:.|..|||.|.:.|  ||.....||.|..|.|.: |
  Rat   422 GADFSTKDADNDNCM-CKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYS 485

  Fly   466 LKRVRWMIRPI 476
            |:....||||:
  Rat   486 LRSTTMMIRPL 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	84/216 (39%)
Angpt1	XP_006241671.1	COG4372	<55..>255	CDD:226809	34/180 (19%)
Angpt1	XP_006241671.1	FReD	281..496	CDD:238040	88/242 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810