Protein Alignment CG10359 and Tnxb

DIOPT Version :10

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001415265.1
• Gene: Tnxb / 81877
• MGIID: 1932137
• Length: 4361
• Species: Mus musculus
• Alignment Length: 328
• Identity: 96/328 - (29%)
• Similarity: 150/328 - (45%)
• Gaps: 66/328 - (20%)

  Fly   180 SQEQYPSSGIGTFNESNLNLSSRLDALAT--------LLASTALSVRSVQVEVANLSRAIRRQSR 236
            ::|..|.:.:.|:.|..:..:..|.:..|        ||.:...|.|.:::..:....|   |.|
Mouse  4058 AKEVTPRTALLTWTEPEVPPTGYLLSFDTPGGQIQEILLPAGTTSHRLLRLFPSTFYSA---QLR 4119

  Fly   237 LIQGKGLRSTPGQQPIF--YGPSGL-------------NGPTATRQLPSSCSYSFLSNHGILKVQ 286
            .|.|:.|  ||   |:.  :...||             |||:|     |..:..||:.:
Mouse  4120 AIWGESL--TP---PVLTSFTTGGLRIPFPRDCGEELKNGPSA-----SKTTTIFLNGN------ 4168

  Fly   287 LTPESESFYVSCDED-----WTVILSRTSDDVNFERGWLDYRDGFGNLAGDFFIGLNKLHALTSS 346
               ......|.||.:     |.|...|.....:|.|.|.:|..||||::|:|::|...||:||.:
Mouse  4169 ---RERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYAHGFGNISGEFWLGNEALHSLTQA 4230

  Fly   347 ALHELRIVMEDFSGNVA-YAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAGDSLSYHAGAKFSTV 410
            ..:.||:.:.  :|..| :|.|..|.:.|.||.|.|.|.|     ...:||||:|||:|:.||..
Mouse  4231 GDYSLRVDLR--AGKEAVFAQYDFFRVDSAKENYRLHLEG-----YHGTAGDSMSYHSGSVFSAR 4288

  Fly   411 DQDNDNCLECNCALRHKGAGWFNNCAKSNLFGEY--TTQNQPGETGIWWDTFSG-QNSLKRVRWM 472
            |:|.:|.| .:||:.::||.|:.||..:||.|.|  |..:|    |:.|..:.| :.|:......
Mouse  4289 DRDPNNLL-ISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQ----GVSWYHWKGFEFSVPFTEMK 4348

  Fly   473 IRP 475
            :||
Mouse  4349 LRP 4351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	71/218 (33%)
Tnxb	NP_001415265.1	EGF_2	177..200	CDD:400365
		EGF_2	208..231	CDD:400365
		EGF_Tenascin	236..262	CDD:480934
		EGF_Tenascin	267..293	CDD:480934
		EGF_Tenascin	298..325	CDD:480934
		C_rich_MXAN6577	301..432	CDD:469225
		EGF_Tenascin	422..448	CDD:480934
		EGF_2	456..479	CDD:400365
		EGF_Tenascin	484..510	CDD:480934
		EGF_Tenascin	515..542	CDD:480934
		EGF_Tenascin	546..572	CDD:480934
		C_rich_MXAN6577	581..690	CDD:469225
		EGF_Tenascin	706..732	CDD:480934
		fn3	737..818	CDD:394996
		fn3	830..906	CDD:394996
		FN3	1076..1138	CDD:473895
		fn3	1292..1369	CDD:394996
		FN3	1386..1466	CDD:238020
		fn3	1484..1557	CDD:394996
		fn3	1599..1676	CDD:394996
		fn3	1707..1777	CDD:394996
		fn3	1801..1881	CDD:394996
		fn3	1904..1971	CDD:394996
		fn3	2000..2067	CDD:394996
		fn3	2102..2164	CDD:394996
		FN3	2211..2279	CDD:238020
		fn3	2315..2395	CDD:394996
		fn3	2426..2496	CDD:394996
		fn3	2522..2602	CDD:394996
		fn3	2636..2709	CDD:394996
		fn3	2748..2825	CDD:394996
		fn3	2861..2931	CDD:394996
		fn3	2970..3045	CDD:394996
		fn3	3076..3146	CDD:394996
		fn3	3183..3260	CDD:394996
		FN3	3259..3691	CDD:442628
		fn3	3569..3644	CDD:394996
		fn3	3679..3752	CDD:394996
		fn3	3773..3855	CDD:394996
		FN3	<3842..>4086	CDD:442628	5/27 (19%)
		FN3	3876..3955	CDD:238020
		fn3	4052..4129	CDD:394996	18/78 (23%)
		Fibrinogen_C	4143..4352	CDD:395095	75/235 (32%)