Protein Alignment CG10359 and ANGPT4

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_057069.1
• Gene: ANGPT4 / 51378
• HGNCID: 487
• Length: 503
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 145/524 - (27%)
• Similarity: 220/524 - (41%)
• Gaps: 114/524 - (21%)

  Fly    10 TVMVLAAICGFGTGSVLEVPGVTQAPPLPPRNLRNNQTRSRIPNNFRSIATP---PIAPRCDYKE 71
            |::|....|.:    ...:|.....|| .|...|::.|..|     .|:|.|   ...|....|:
Human    35 TLVVQHGHCSY----TFLLPKSEPCPP-GPEVSRDSNTLQR-----ESLANPLHLGKLPTQQVKQ 89

  Fly    72 LMTNLHDRVGILVTLDED----QRHRLEVIDKKLDQ------------LVESSSA---RMESMKA 117
            |...|.:....|..|:..    .|.:||.:.:::.|            |:..::|   ::..|:|
Human    90 LEQALQNNTQWLKKLERAIKTILRSKLEQVQQQMAQNQTAPMLELGTSLLNQTTAQIRKLTDMEA 154

  Fly   118 QQLDFLHRLDSFEHIQRLSRNTLDELKGETDQVFGPRNVRELKHKLRNRKKMKDISRTVRDVSQE 182
            |.|:...|:|:......||.|.|:                  ...|..|:|::.:        |.
Human   155 QLLNQTSRMDAQMPETFLSTNKLE------------------NQLLLQRQKLQQL--------QG 193

  Fly   183 QYPSSGIGTFNESNLNLSSRLDALATLLASTALSVRSVQVEVAN-LS-------------RAIRR 233
            |            |..|..||.||.|.......|:.|.:.::.| ||             |.:|.
Human   194 Q------------NSALEKRLQALETKQQEELASILSKKAKLLNTLSRQSAALTNIERGLRGVRH 246

  Fly   234 QSRLIQGKG---------LRSTPGQQPIFYGPSGLNGPTATRQLPSSCS---YSFLSNHGILKVQ 286
            .|.|:|.:.         ||....::.....|:.:   .|..|:...|:   .|..|..|:..:|
Human   247 NSSLLQDQQHSLRQLLVLLRHLVQERANASAPAFI---MAGEQVFQDCAEIQRSGASASGVYTIQ 308

  Fly   287 LTPESESFYVSCDED-----WTVILSRTSDDVNFERGWLDYRDGFGNLAGDFFIGLNKLHALTSS 346
            ::..::...|.||..     ||:|..|.:..|||:|.|.||:.|||:.||:.::|...:|.||..
Human   309 VSNATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRNWKDYKQGFGDPAGEHWLGNEVVHQLTRR 373

  Fly   347 ALHELRIVMEDFSGNVAYAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAG-DSLSYHAGAKFSTV 410
            |.:.||:.::|:.|:.|||.|..|.:|||.:||.|.::|     .:.||| .|........|||:
Human   374 AAYSLRVELQDWEGHEAYAQYEHFHLGSENQLYRLSVVG-----YSGSAGRQSSLVLQNTSFSTL 433

  Fly   411 DQDNDNCLECNCALRHKGAGWFNNCAKSNLFGEY--TTQNQPGETGIWWDTFSGQN-SLKRVRWM 472
            |.|||:|| |.||....|..||:.|..|||.|.|  ...|:....||.|..|.|.: ||:..|.|
Human   434 DSDNDHCL-CKCAQVMSGGWWFDACGLSNLNGVYYHAPDNKYKMDGIRWHYFKGPSYSLRASRMM 497

  Fly   473 IRPI 476
            |||:
Human   498 IRPL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	83/220 (38%)
ANGPT4	NP_057069.1	FReD	288..501	CDD:238040	82/218 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810