DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10359 and Fga

DIOPT Version :9

Sequence 1:	NP_001137882.1	Gene:	CG10359 / 38434	FlyBaseID:	FBgn0035452	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001008724.1	Gene:	Fga / 361969	RGDID:	2603	Length:	782	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	112/392 - (28%)
Similarity:	162/392 - (41%)	Gaps:	95/392 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 FLHRLDSFEHIQRLSRNTLDELKGETDQVFG--PRNVRELKHKLRNRKKMKDISRTVRDVSQEQY 184
            |..|||....:.       .||....|..||  ..|.:|...|..:.....||          :.
  Rat   446 FSGRLDELSRMH-------PELGSFYDSRFGSLTSNFKEFGSKTSDSDIFTDI----------EN 493

  Fly   185 PSSGIGTFNESNLNLSSRLDA-----LATLLASTALSVRSVQVEVANLSRAIRRQSRLIQGKGLR 244
            |||.:..|:.|:...:.|...     :|...||.|......:......:|.:|....::|..
  Rat   494 PSSHVPEFSSSSKTSTVRKQVTKSYKMADEAASEAHQEGDTRTTKRGRARTMRDCDDVLQTH--- 555

  Fly   245 STPGQQPIFYGPSGLNGPTATRQLPSSCSYSFLSNHGILKVQLTPESESFYVSCDED-----WTV 304
                       |||                   :.:||..::|...|:.|.|.||::     |.:
  Rat   556 -----------PSG-------------------AQNGIFSIKLPGSSKIFSVYCDQETSLGGWLL 590

  Fly   305 ILSRTSDDVNFERGWLDYRDGFGNL----AGDFFIGLNKLHALTSSALHELRIVMEDFSGNVAYA 365
            |..|....:||.|.|.||:.|||:|    .|:|::|.:.||.||... ..||:.:||::|..|||
  Rat   591 IQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRG-SVLRVELEDWAGKEAYA 654

  Fly   366 GYSLFAIGSEKELYPLVLLGKFQDNLTPSAGDSL-----------SYHAGAKFSTVDQDNDNCLE 419
            .|. |.:|||.|.|.| .:..:|.    :|||:|           :.|:..:|||.|:|.|...|
  Rat   655 EYH-FRVGSEAEGYAL-QVSSYQG----TAGDALMEGSVEEGTEYTSHSNMQFSTFDRDADQWEE 713

  Fly   420 CNCALRHKGAGWFNNCAKSNLFGEY-------TTQNQPG--ETGIWWDTFSGQN-SLKRVRWMIR 474
             |||..:.|..|:|:|..:||.|.|       ...|.|.  |.|:.|..|.|.: ||:.||..||
  Rat   714 -NCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIR 777

  Fly   475 PI 476
            |:
  Rat   778 PL 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	81/238 (34%)
Fga	NP_001008724.1	Fib_alpha	51..189	CDD:285864
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..374
		Fibrinogen_aC	388..453	CDD:288972	4/6 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	522..542		3/19 (16%)
		FReD	546..779	CDD:238040	86/273 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900