Protein Alignment CG10359 and Tnn

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_808507.2
• Gene: Tnn / 329278
• MGIID: 2665790
• Length: 1560
• Species: Mus musculus
• Alignment Length: 494
• Identity: 131/494 - (26%)
• Similarity: 202/494 - (40%)
• Gaps: 134/494 - (27%)

  Fly    32 TQAPPL--PPRNLRNNQTRSRIPNNFRSIATPPIAPRCD------------YKELMTNLHDRVGI 82
            |:||..  .|:||..|    |:..|..:|:..|:....|            .||:..:......|
Mouse  1141 TKAPTEIDSPKNLVTN----RVTENTATISWDPVRANIDRYMVRYTSADGETKEIPVSKDQSSTI 1201

  Fly    83 LVTLDEDQRHRLEVIDKKLDQLVESSSARMESMKAQQLDFLHRLDSFEHIQRLSRNTLDELKGET 147
            |..|.....:.:.|..:|        .|| ||.||                        :.|..|
Mouse  1202 LTGLKPGMEYTIHVWAQK--------GAR-ESKKA------------------------DTKALT 1233

  Fly   148 DQVFGPRNVRE--LKHKLRNRKKMKDISRTVRDVSQEQYPSSGIGTFNESNLNLSSRLDALATLL 210
             ::..|||:|.  :.|                        |.|:.|:    |..|:::|......
Mouse  1234 -EIDPPRNLRPFGVTH------------------------SGGVLTW----LPPSAQIDGYILTY 1269

  Fly   211 ASTALSVRSVQV-------EVANLSRAIRRQSRLIQGKGLR-----STPGQQPIFYGPSGLNGPT 263
            .....:|:.|::       |:.:|.:.:.....|:..||.:     ||.           |:...
Mouse  1270 QFPNGTVKEVELPRGQQRFELQDLEQGVTYPVSLVAFKGNQRSRTVSTT-----------LSTVD 1323

  Fly   264 ATRQLPSSCSYSFLSNH---GILKVQLTPE-SESFYVSCDED-----WTVILSRTSDDVNFERGW 319
            |....||.||....:.:   |:..:.|..: |....|.||.|     |.|...|.:..::|.:.|
Mouse  1324 ARFPHPSDCSQVQQNTNAASGLYTIYLNGDASRPMQVYCDMDTDGGGWIVFQRRNTGQLDFFKRW 1388

  Fly   320 LDYRDGFGNLAGDFFIGLNKLHALT--SSALHELRIVMEDFSGNVAYAGYSLFAIGSEKELYPLV 382
            ..|.:|||:...:|::||:|||.||  ::..:|:|..::.|:.: |||.|..|.:.|.||.|.|
Mouse  1389 RSYVEGFGDPMKEFWLGLDKLHNLTTGTTTRYEVRADLQTFNES-AYAVYDFFQVASSKERYKL- 1451

  Fly   383 LLGKFQDNLTPSAGDSLSYHAGAKFSTVDQDNDNCLECNCALRHKGAGWFNNCAKSNLFGEYTTQ 447
            .:||::.    :|||:|:||.|.||:|.|:|||..|. ||||.|.|..|:.||..:|..|:|
Mouse  1452 SVGKYRG----TAGDALTYHNGWKFTTFDRDNDIALS-NCALTHHGGWWYKNCHLANPNGKY--- 1508

  Fly   448 NQPGET----GIWWDTFSGQN-SLKRVRWMIRPISEGID 481
               |||    |:.|:.:.|.. |:..|...|||.....|
Mouse  1509 ---GETKHSEGVNWEPWKGHEFSIPYVELKIRPFGYSRD 1544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	80/224 (36%)
Tnn	NP_808507.2	EGF_2	<142..166	CDD:285248
		EGF_2	169..197	CDD:285248
		EB	181..233	CDD:279949
		EGF_2	233..259	CDD:285248
		fn3	264..332	CDD:278470
		fn3	359..434	CDD:278470
		fn3	444..521	CDD:278470
		FN3	532..608	CDD:214495
		FN3	620..696	CDD:214495
		fn3	708..785	CDD:278470
		fn3	796..875	CDD:278470
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	868..888
		fn3	884..961	CDD:278470
		fn3	972..1049	CDD:278470
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1044..1063
		FN3	1060..1136	CDD:214495
		fn3	1148..1225	CDD:278470	19/89 (21%)
		fn3	1236..1313	CDD:278470	18/104 (17%)
		FReD	1327..1539	CDD:238040	80/224 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100073
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.710