Protein Alignment CG10359 and ANGPT2

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001138.1
• Gene: ANGPT2 / 285
• HGNCID: 485
• Length: 496
• Species: Homo sapiens
• Alignment Length: 495
• Identity: 130/495 - (26%)
• Similarity: 201/495 - (40%)
• Gaps: 93/495 - (18%)

  Fly    53 NNFR----SIATPPIAPR---CDYKELMTNLHD-------RVGILVTLD-----EDQRHRLEVID 98
            ||||    ||.......:   |.|..|:..:.:       .|...|..|     :|...||:|::
Human    20 NNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLE 84

  Fly    99 K----------KLDQLVESSSARMESMKAQQLDFLHRLDSFEHI-QRLSRNTLDELKGETD---Q 149
            .          ||:..:: .:.:.|.::.||....::......| ..|...|.::.:..||   |
Human    85 NIMENNTQWLMKLENYIQ-DNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQ 148

  Fly   150 VFGPRNVRE---LKHKLRNRKKMKDISRTVRDVSQEQYPSSGIGTFNESNLNLSSRLDALATLLA 211
            |.......|   |:|.|...|..|.|.....::::.|          :.|..|..::.|:..
Human   149 VLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQ----------DKNSFLEKKVLAMED--- 200

  Fly   212 STALSVRSVQVEVANLSRAIRRQSRLI-------------------QGKGLRSTPGQQPIFYGPS 257
            ...:.::|::.|...|...:.:|:.:|                   |...|..|..........|
Human   201 KHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTS 265

  Fly   258 -GLNGPTATRQLPSS---CSYSFLSNH---GILKVQLTPESESFYVSCDED-----WTVILSRTS 310
             ....||..::...|   |:..|.|.|   ||..:.....:|.....||.:     ||:|..|..
Human   266 NSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRRED 330

  Fly   311 DDVNFERGWLDYRDGFGNLAGDFFIGLNKLHALTSSALHELRIVMEDFSGNVAYAGYSLFAIGSE 375
            ..|:|:|.|.:|:.||||.:|::::|...:..||:...:.|:|.::|:.||.||:.|..|.:.||
Human   331 GSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSE 395

  Fly   376 KELYPLVLLGKFQDNLTPSAG--DSLSYHAGAKFSTVDQDNDNCLECNCALRHKGAGWFNNCAKS 438
            :..|.:.|.|     ||.:||  .|:| ..|..|||.|.|||.|: |.|:....|..||:.|..|
Human   396 ELNYRIHLKG-----LTGTAGKISSIS-QPGNDFSTKDGDNDKCI-CKCSQMLTGGWWFDACGPS 453

  Fly   439 NLFGEYTTQNQPGE--TGIWWDTFSGQN-SLKRVRWMIRP 475
            ||.|.|..|.|...  .||.|..:.|.. |||....||||
Human   454 NLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	80/225 (36%)
ANGPT2	NP_001138.1	SMC_N	<78..>295	CDD:330553	42/230 (18%)
		FBG	280..494	CDD:214548	80/221 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810