Protein Alignment CG10359 and ANGPT1

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001137.2
• Gene: ANGPT1 / 284
• HGNCID: 484
• Length: 498
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 134/466 - (28%)
• Similarity: 205/466 - (43%)
• Gaps: 115/466 - (24%)

  Fly    40 RNLRNNQTRSRIPNNFRSIATPPIAPRCDYKELMTNLHDRVGILVTLDEDQRHRLEVIDKKLDQL 104
            :|...|.|.:.:     .|.|..::...:....:|::..:|       .:|..|||:      ||
Human   117 QNAVQNHTATML-----EIGTSLLSQTAEQTRKLTDVETQV-------LNQTSRLEI------QL 163

  Fly   105 VES--SSARMESMKAQQLD---FLHRLDS-FEH----IQRLSRNTLDELKGETDQVFG--PRN-- 155
            :|:  |:.::|....||.:   .:|..:| .||    ::...:..||.||.|.:.:.|  .|.
Human   164 LENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTY 228

  Fly   156 -VRELKHKLRNRKKMKDISRTVRDVSQEQYPSSGIGTFNESNLNLSSRLDALATLLASTALSVRS 219
             ::||:.:| ||      :.|...|.|:|                  :|:.:.|
Human   229 IIQELEKQL-NR------ATTNNSVLQKQ------------------QLELMDT----------- 257

  Fly   220 VQVEVANLSRAIRRQSRLIQG------KGLRSTPGQQPIFYGPSGLNGPTATRQLPSSCSYSFLS 278
                |.||.....::..|::|      |..|.........:..||:              |:...
Human   258 ----VHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGI--------------YTIYI 304

  Fly   279 NHGILKVQLTPESESFYVSCDED---WTVILSRTSDDVNFERGWLDYRDGFGNLAGDFFIGLNKL 340
            |:       .||.:..:.:.|.:   ||||..|....::|:|||.:|:.||||.:|::::|...:
Human   305 NN-------MPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFI 362

  Fly   341 HALTSSALHELRIVMEDFSGNVAYAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAG--DSLSYHA 403
            .|:||...:.|||.:.|:.||.||:.|..|.||:||:.|.|.|.|.     |.:||  .||..|
Human   363 FAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRLYLKGH-----TGTAGKQSSLILH- 421

  Fly   404 GAKFSTVDQDNDNCLECNCALRHKGAGWFNNCAKSNLFGEYTT--QNQPGETGIWWDTFSGQN-S 465
            ||.|||.|.|||||: |.|||...|..||:.|..|||.|.:.|  ||.....||.|..|.|.: |
Human   422 GADFSTKDADNDNCM-CKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYS 485

  Fly   466 LKRVRWMIRPI 476
            |:....||||:
Human   486 LRSTTMMIRPL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	84/216 (39%)
ANGPT1	NP_001137.2	Smc	<81..280	CDD:224117	45/220 (20%)
		FReD	281..496	CDD:238040	88/242 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810