Protein Alignment CG10359 and FGG

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_068656.2
• Gene: FGG / 2266
• HGNCID: 3694
• Length: 453
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 102/438 - (23%)
• Similarity: 174/438 - (39%)
• Gaps: 104/438 - (23%)

  Fly    96 VIDKKLDQLVESSSARMESMKAQQLDFLHRLDSFEHIQRLSRNTLDELKG---------ETDQVF 151
            ::|::......::....:.:...|......|.|.|.|.....|...|:|.         ..|:..
Human    36 ILDERFGSYCPTTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDESS 100

  Fly   152 GPRNVRELKHKLRNRKKMKDI-----SRTVRDVS----QEQYPSSGIGTFNESNLNLSSRLDALA 207
            .|..:...  .|::||.:::|     |....|.|    ||.|.|:     |:..:||..:   :|
Human   101 KPNMIDAA--TLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSN-----NQKIVNLKEK---VA 155

  Fly   208 TLLASTALSVRSVQVEVANLSRAIRRQSRLIQGKGLRSTPGQQPIFYGPSGLNGPTATRQLPSSC 272
            .|.|......:.. |::.:::   .:..:.|..||.:.:
Human   156 QLEAQCQEPCKDT-VQIHDIT---GKDCQDIANKGAKQS-------------------------- 190

  Fly   273 SYSFLSNHGILKVQLTPESESFYVSCDED-----WTVILSRTSDDVNFERGWLDYRDGFGNLA-- 330
                    |:..::....::.|.|.|:.|     |||...|....|:|::.|:.|::|||:|:
Human   191 --------GLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPT 247

  Fly   331 --GDFFIGLNKLHAL-TSSAL-HELRIVMEDFSGNVAYAGYSLFAIGSEKELYPLVLLGKFQDNL 391
              .:|::|..|:|.: |.||: :.||:.:||::|..:.|.|::|.:|.|.:.|.|. ...|....
Human   248 GTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLT-YAYFAGGD 311

  Fly   392 TPSAGDSLSY-----------HAGAKFSTVDQDNDNCLECNCALRHKGAGWFNNCAKSNL----- 440
            ...|.|...:           |.|.:|||.|.|||. .|.|||.:.....|.|.|...:|
Human   312 AGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDK-FEGNCAEQDGSGWWMNKCHAGHLNGVYY 375

  Fly   441 -FGEYTTQNQPG--ETGIWWDTFSGQ-NSLKRVRWMIRP-----ISEG 479
             .|.|:..:.|.  :.||.|.|:..: .|:|:....|.|     |.||
Human   376 QGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEG 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	67/244 (27%)
FGG	NP_068656.2	Fib_alpha	31..172	CDD:285864	29/146 (20%)
		FReD	175..414	CDD:294064	69/277 (25%)
		Gamma-chain polymerization, binding amino end of another fibrin alpha chain	400..422		5/21 (24%)
		Platelet aggregation and Staphylococcus clumping	423..437		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..453		102/438 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900