Protein Alignment CG10359 and FGB

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_005132.2
• Gene: FGB / 2244
• HGNCID: 3662
• Length: 491
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 115/510 - (22%)
• Similarity: 190/510 - (37%)
• Gaps: 139/510 - (27%)

  Fly    27 EVPGVTQAPPLPPRNLRNNQTRSRIPNNFRSIATPPIAPRCDYKELMTNLHDRVGILVTLDEDQR 91
            |.|.:..|||    .:.....|:|           |.......|::.....|..|.|
Human    55 EAPSLRPAPP----PISGGGYRAR-----------PAKAAATQKKVERKAPDAGGCL-------- 96

  Fly    92 HRLEVIDKKLDQLVESSSARMESMKAQQLDFLHRLDSFEHIQRLSRNTLDELKGETDQVFGPRN- 155
            |    .|..|..|..:.....|::..|              :|..||::|||....:.|....:
Human    97 H----ADPDLGVLCPTGCQLQEALLQQ--------------ERPIRNSVDELNNNVEAVSQTSSS 143

  Fly   156 -------VRELKHKLRNRKKMKDISRTVRDVSQE-----QYPSSGIGTFNESNLNLSSRLDALAT 208
                   :::|..|  .:|::||....|.:.|.|     .|....:      |.|:.:.|..|.:
Human   144 SFQYMYLLKDLWQK--RQKQVKDNENVVNEYSSELEKHQLYIDETV------NSNIPTNLRVLRS 200

  Fly   209 LLASTALSVR------SVQVEVANLSRAIRRQSRLIQGKGLRSTPGQQPIFYGPSGLNGPTATRQ 267
            :|.:....::      |.|:|.......:.....::.||..     ::.|..|     |.|:...
Human   201 ILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKEC-----EEIIRKG-----GETSEMY 255

  Fly   268 LPSSCSYSFLSNHGILKVQLTPES--ESFYVSCDED-----WTVILSRTSDDVNFERGWLDYRDG 325
            |                  :.|:|  :.:.|.||.:     ||||.:|....|:|.|.|..|:.|
Human   256 L------------------IQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQG 302

  Fly   326 FGNLA------------GDFFIGLNKLHALTSSALHELRIVMEDFSGNVAYAGYSLFAIGSEKEL 378
            |||:|            |::::|.:|:..||.....||.|.|||:.|:...|.|..|.:.:|...
Human   303 FGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANK 367

  Fly   379 YPLVLLGKFQ--------DNLTPSAGD--SLSYHAGAKFSTVDQDNDNCLECN----CALRHKGA 429
            |. :.:.|::        |..:...|:  :::.|.|..|||.|:|||..|..:    |:....|.
Human   368 YQ-ISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGG 431

  Fly   430 GWFNNCAKSNLFGEYTTQNQ--------PGETGIWWDTFSGQ-NSLKRVRWMIRP 475
            .|:|.|..:|..|.|....|        ..:.|:.|..:.|. .|::::...|||
Human   432 WWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	67/251 (27%)
FGB	NP_005132.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..75		7/34 (21%)
		Beta-chain polymerization, binding distal domain of another fibrin	45..47
		Fib_alpha	92..234	CDD:312286	32/175 (18%)
		FReD	237..486	CDD:294064	71/277 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810