DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10359 and Fga

DIOPT Version :9

Sequence 1:NP_001137882.1 Gene:CG10359 / 38434 FlyBaseID:FBgn0035452 Length:485 Species:Drosophila melanogaster
Sequence 2:NP_001104518.1 Gene:Fga / 14161 MGIID:1316726 Length:789 Species:Mus musculus


Alignment Length:528 Identity:143/528 - (27%)
Similarity:202/528 - (38%) Gaps:148/528 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 FGTGSVLEVPGVTQAPPLPPRNLRNNQTRSRIPN-----NFRSIATPPIAPRCDY---------- 69
            :||||           |.|..:..|  .|...||     .|...::|  |.|.:|          
Mouse   336 WGTGS-----------PRPGSDSGN--FRPANPNWGVFSEFGDSSSP--ATRKEYHTGKAVTSKG 385

  Fly    70 -KELMTNLHDRVGILVTLDEDQRHRLEVIDKKLDQLVESSSARMESMK-------------AQQL 120
             |||:.....    :.:......||  ...|.:.:.|.....|.|.:|             |.:|
Mouse   386 DKELLIGKEK----VTSSGTSTTHR--SCSKTITKTVTGPDGRREVVKEVITSDDGSDCGDATEL 444

  Fly   121 DFLHRLDSFEHIQRLSRNTLDE-------LKGETDQVFG--PRNVRELKHKLRNRKKMKDISRTV 176
            |..|   ||.       .:|||       |.|..|..||  ..|.:|...|..:.   .||...:
Mouse   445 DISH---SFS-------GSLDELSERHPDLSGFFDNHFGLISPNFKEFGSKTHSD---SDILTNI 496

  Fly   177 RDVSQEQYPSSGIGTFNESNLNLSSRLDALATL-LASTALSVRSVQVEVANL--SRAIRRQSRLI 238
            .|      |||.:..|:.|:...:.:.....|. :|..|.|....:.|..|.  .||..|.:|..
Mouse   497 ED------PSSHVPEFSSSSKTSTVKKQVTKTYKMADEAGSEAHREGETRNTKRGRARARPTRDC 555

  Fly   239 QGKGLRSTPGQQPIFYGPSGLNGPTATRQLPSSCSYSFLSNHGILKVQLTPESESFYVSCDED-- 301
            .......|.|.|                             :||..::....|:.|.|.||::  
Mouse   556 DDVLQTQTSGAQ-----------------------------NGIFSIKPPGSSKVFSVYCDQETS 591

  Fly   302 ---WTVILSRTSDDVNFERGWLDYRDGFGNL----AGDFFIGLNKLHALTSSALHELRIVMEDFS 359
               |.:|..|....:||.|.|.||:.|||:|    .|:|::|.:.||.||... ..||:.:||::
Mouse   592 LGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRG-SVLRVELEDWA 655

  Fly   360 GNVAYAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAGDSL-----------SYHAGAKFSTVDQD 413
            |..|||.|. |.:|||.|.|.|.:     .:...:|||:|           :.|:..:|||.|:|
Mouse   656 GKEAYAEYH-FRVGSEAEGYALQV-----SSYRGTAGDALVQGSVEEGTEYTSHSNMQFSTFDRD 714

  Fly   414 NDNCLECNCALRHKGAGWFNNCAKSNLFGEY-------TTQNQPG--ETGIWWDTFSGQN-SLKR 468
            .|...| |||..:.|..|:|:|..:||.|.|       ...|.|.  |.|:.|..|.|.: ||:.
Mouse   715 ADQWEE-NCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRA 778

  Fly   469 VRWMIRPI 476
            ||..|||:
Mouse   779 VRMKIRPL 786

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10359NP_001137882.1 FReD 267..476 CDD:238040 79/238 (33%)
FgaNP_001104518.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 263..420 22/104 (21%)
Fibrinogen_aC 392..457 CDD:288972 15/80 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 526..555 9/28 (32%)
FReD 550..786 CDD:238040 84/272 (31%)
Fib_alpha 51..190 CDD:285864
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2579
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.