Protein Alignment CG10359 and FGL2

DIOPT Version :9

• Sequence 1: NP_001137882.1
• Gene: CG10359 / 38434
• FlyBaseID: FBgn0035452
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_006673.1
• Gene: FGL2 / 10875
• HGNCID: 3696
• Length: 439
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 121/474 - (25%)
• Similarity: 191/474 - (40%)
• Gaps: 135/474 - (28%)

  Fly    37 LPPRNLRNNQTRSRIPNNFRSIATPPIAPRCDYKELMTNLHDRVGILVTLDEDQRHRLEVIDK-- 99
            |||..::..:..|||...|:.:.        :.||::.:|....         |..:|:..|.
Human    61 LPPLTIQLPKQFSRIEEVFKEVQ--------NLKEIVNSLKKSC---------QDCKLQADDNGD 108

  Fly   100 --KLDQLVESSSARMESMKAQQLDFLHRLDSFEHIQRLSRNTLDELKGETDQVFGPRNVRELKHK 162
              :...|:.|:.|..|                     :..|.:.||:.|         |.:|..:
Human   109 PGRNGLLLPSTGAPGE---------------------VGDNRVRELESE---------VNKLSSE 143

  Fly   163 LRNRKKMKDISRTVRDVSQEQYPSSGIGTFNESNL----NLSSRLDALATLLASTALSVRSVQVE 223
            |:|.|:..::..               |...:.||    |:.:.:|:                 :
Human   144 LKNAKEEINVLH---------------GRLEKLNLVNMNNIENYVDS-----------------K 176

  Fly   224 VANLSRAIR----RQSRLIQGKGLRSTPGQQPIFYGPSGLNGPTATRQLPSSCS-YSFLSNHGIL 283
            ||||:..:.    :.|:....:.::|.|.|..|:                ..|| |..:......
Human   177 VANLTFVVNSLDGKCSKCPSQEQIQSRPVQHLIY----------------KDCSDYYAIGKRSSE 225

  Fly   284 KVQLTPE--SESFYVSCDED-----WTVILSRTSDDVNFERGWLDYRDGFGNLAGDFFIGLNKLH 341
            ..::||:  :.||.|.||.:     |||:.:|.....||.|.|.||:.|||||..:|::|.:|:|
Human   226 TYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIH 290

  Fly   342 ALTSSALHELRIVMEDFSGNVAYAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAGDSLSY----- 401
            .||.|....|||.:|||:|...||.|..|.:.:|...|.|.:     .|...:|||:|.:
Human   291 LLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHV-----GNYNGTAGDALRFNKHYN 350

  Fly   402 HAGAKFSTVDQDNDNCLECNCALRHKGAGWFNNCAKSNLFGEYTTQNQPG-ETGIWWDTFSG--- 462
            |....|:|.|:|||.....||.|.:....||:.|..:||.|:|..|...| ..||:|.|:.|
Human   351 HDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSE 415

  Fly   463 ------QNSLKRVRWMIRP 475
                  ::|.|..:.||||
Human   416 AHPGGYKSSFKEAKMMIRP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	81/232 (35%)
FGL2	NP_006673.1	DUF460	<28..>161	CDD:331991	27/161 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..126		5/43 (12%)
		FReD	209..435	CDD:294064	82/247 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810