DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10359 and fgl2

DIOPT Version :9

Sequence 1:	NP_001137882.1	Gene:	CG10359 / 38434	FlyBaseID:	FBgn0035452	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_002933134.2	Gene:	fgl2 / 100494596	XenbaseID:	XB-GENE-482375	Length:	429	Species:	Xenopus tropicalis

Alignment Length:	394	Identity:	104/394 - (26%)
Similarity:	168/394 - (42%)	Gaps:	100/394 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 PRNVRELKHKLRNRKKMKDISRTVRDVSQ---------------EQYPSSGIGTFNESNLNLSSR 202
            |:..:.|:..::..:.:|:|...::...|               :|.|.|..|..:.:...|.|:
Frog    64 PKQFQLLEKTIKEVQSLKEIVNALKKSCQDCKLQADDTPEKDNGQQNPESTNGDQDNNIHELQSK 128

  Fly   203 LDALATLLASTALSVRSVQVEVANLSRAIRRQSRLIQGKGLRSTPGQQPI-------FYGPSGLN 260
            :..::..|.:....:.|:|.::..:|                      ||       :.....:|
Frog   129 VKKMSISLKNARNQINSLQEQLGKMS----------------------PINMNTIEQYVDTKMIN 171

  Fly   261 GPTATRQLPSSCSYSFLSNHGILK----VQL---------------------TPE--SESFYVSC 298
            ...|...|.:.||    ||..:|:    :||                     ||:  :::|.|.|
Frog   172 LSFALNNLDNKCS----SNCPVLEANPSIQLLYKDCSDYYKIGKKVDGRYRVTPDEKNKTFEVYC 232

  Fly   299 DED-----WTVILSRTSDDVNFERGWLDYRDGFGNLAGDFFIGLNKLHALTSSALHELRIVMEDF 358
            |.:     |||:..|.....:|.|.|.:|::|||||.|:|::|.:|||.||.|....|||.:|||
Frog   233 DMESMGGGWTVVQIRKDGSTSFNRTWNEYKNGFGNLTGEFWLGNDKLHLLTKSTDMILRIELEDF 297

  Fly   359 SGNVAYAGYSLFAIGSEKELYPLVLLGKFQDNLTPSAGDSLSY-----HAGAKFSTVDQDNDNCL 418
            .||..||.|..|.:.:|...|.|.:.|     .:.:|||:|.:     |....|:|.|:|||...
Frog   298 KGNREYAKYDQFYVANEYLKYRLTIGG-----YSGTAGDALHFSKQYNHDQKFFTTPDKDNDRYP 357

  Fly   419 ECNCALRHKGAGWFNNCAKSNLFGEYTTQNQPG-ETGIWWDTFSG---------QNSLKRVRWMI 473
            ..||...:....||:.|..:||.|:|...:..| ..||:|.|::|         :.:.|.|:.||
Frog   358 SGNCGSYYSSGWWFDACMSANLNGKYYKNDYKGVRNGIFWGTWTGVSDEHLNSYRQTFKFVKMMI 422

  Fly   474 RPIS 477
            ||.|
Frog   423 RPKS 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10359	NP_001137882.1	FReD	267..476	CDD:238040	83/255 (33%)
fgl2	XP_002933134.2	Smc	<53..164	CDD:224117	17/121 (14%)
fgl2	XP_002933134.2	FReD	199..425	CDD:238040	75/230 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910