Protein Alignment Eip63E and CDK1

DIOPT Version :9

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001307847.1
• Gene: CDK1 / 983
• HGNCID: 1722
• Length: 297
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 145/307 - (47%)
• Similarity: 195/307 - (63%)
• Gaps: 21/307 - (6%)

  Fly   203 EAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQ-EEEGAPFTAIREASLLKELKHSNIVTL 266
            |.|.|:|.:|||:|..||||..|.|.|.||:|:|||: ||||.|.|||||.||||||:|.|||:|
Human     2 EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSL 66

  Fly   267 HDIVHTRETLTFVFEYVNTDLSQYMEKHPGG--LDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKP 329
            .|::.....|..:||:::.||.:|::..|.|  :|...|:.:|:|:|:|:.:||.|||||||:||
Human    67 QDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKP 131

  Fly   330 QNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVE 394
            |||||.|.|.:||||||||||..:|...|:|||||||||.|:|||||..|||.:|:|.:|.||.|
Human   132 QNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAE 196

  Fly   395 MVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGV-------THFPGYKPHKLGFYRPRKLGHN 452
            :.|..|.|.|..: .|||.:||:.||||..:.||.|       ..||.:||..|..: .:.|..|
Human   197 LATKKPLFHGDSE-IDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASH-VKNLDEN 259

  Fly   453 FPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYEL 499
                     |..:.:..|..:|.:|:....||.||||..|..::.::
Human   260 ---------GLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	PLN00009	203..492	CDD:177649	144/298 (48%)
		STKc_PCTAIRE_like	204..489	CDD:270835	141/294 (48%)
CDK1	NP_001307847.1	STKc_CDK1_euk	3..287	CDD:270845	141/294 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820