Protein Alignment Eip63E and CAK1

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_116624.1
• Gene: CAK1 / 850515
• SGDID: S000001865
• Length: 368
• Species: Saccharomyces cerevisiae
• Alignment Length: 331
• Identity: 74/331 - (22%)
• Similarity: 126/331 - (38%)
• Gaps: 98/331 - (29%)

  Fly   245 PFTAIREASLLKEL----KH------SNIVTLHDIVHTRETLTFVFEYVNTDLSQYM-------- 291
            |..|..|.|:|.:|    ||      |.....:|::     |.|.||.:|  |.::|
Yeast    41 PHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLL-----LLFPFEEMN--LYEFMQMHYKRDR 98

  Fly   292 ----------------------EKHPGGLDHRNVRLFLF-QLLRGLSYCHKRRVLHRDVKPQNLL 333
                                  :|:...||.....|..| |::.|:::.|:.:::|||:||||::
Yeast    99 RKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIM 163

  Fly   334 ISD-----CGELKLADFGL-------ARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMW 386
            :::     ..:|.:.|||:       ::..:.|..:...::.|..|:.|:||.|...|...:|:|
Yeast   164 LTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVW 228

  Fly   387 GVGCI----FVEMVTGMPTFPG-IRDTYDQLD----------KIFKLLGTPTEDTWPGVTHFPGY 436
            .:..|    |....:.|...|. |.|..|.::          .||:.||.|:...|..|... |.
Yeast   229 SLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKWEEVAQH-GS 292

  Fly   437 KPHKLGFYRPRKLG----------------HNFPRLYDIIE---GETIAN---GFLQLNPEQRLG 479
            ....:|.:.....|                .|.|||.:|.:   .:...|   |.:..:|.:|..
Yeast   293 VDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLDEIADVKVKQKFINCILGMVSFSPNERWS 357

  Fly   480 ADDALQ 485
            ....||
Yeast   358 CQRILQ 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	74/331 (22%)
CAK1	NP_116624.1	Protein Kinases, catalytic domain	13..>234	CDD:473864	46/199 (23%)
		Protein Kinases, catalytic domain	<135..363	CDD:473864	51/228 (22%)