Protein Alignment Eip63E and cdk17

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001188286.1
• Gene: cdk17 / 798487
• ZFINID: ZDB-GENE-041210-15
• Length: 526
• Species: Danio rerio
• Alignment Length: 525
• Identity: 235/525 - (44%)
• Similarity: 310/525 - (59%)
• Gaps: 69/525 - (13%)

  Fly    31 QKLKKRLSHSFGRLTI---SREDGD--------ESTHHHHHHHHHRGGH-------------GGH 71
            |.:.:.||....::||   |.:|.:        .|:|..|...|...|.             ||.
Zfish    19 QTIDESLSELAEQMTIEENSSKDSEPIVRNGRPPSSHSMHSFLHQYTGSFKKPPLRRPHSVIGGS 83

  Fly    72 HNHGNKVPYNGYNSEEYLDRLEPNGNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDRVQ 136
            ......:|.||    ..||.:..|..:.:|        .||.:.......:.:|........|..
Zfish    84 LGSFMAMPRNG----SRLDIVHENLKMGSD--------GESDQASGTSSDEVQSPTGVCLRTRSH 136

  Fly   137 RQLSVSSDSKLLD--EDIR------EEMKYHSHVVMRPKKPP--RPKSEVFLNKQETHPRRKRFS 191
            |::|:...:|.|.  .|||      |:::..|        ||  :|.|.        ..||...|
Zfish   137 RRISMEDLNKRLSLPADIRIPDGYLEKLQLSS--------PPFDQPLSR--------RSRRASLS 185

  Fly   192 AFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLK 256
            ..|    |||.|.|:||:.||||:||||:||.||||...||||||||:.|||||.|||||.||||
Zfish   186 EIG----FGKLETYIKLDKLGEGTYATVFKGRSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLK 246

  Fly   257 ELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRR 321
            :|||:|||||||||||.::||.||||::.||.|||:.....:...||::||||:||||:|||:|:
Zfish   247 DLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKIFLFQILRGLAYCHRRK 311

  Fly   322 VLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMW 386
            |||||:|||||||::.|||||||||||||||||:.|||:||||||||||||||||:||||.:|||
Zfish   312 VLHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMW 376

  Fly   387 GVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGH 451
            ||||||.||..|.|.||| ....|:|..||:||||||||.|||::....:|.:....|:|:...:
Zfish   377 GVGCIFYEMAAGRPLFPG-STVEDELHLIFRLLGTPTEDNWPGISSIEEFKSYNFPKYKPQPFIN 440

  Fly   452 NFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEGVQLYTE 516
            :.|||  ..||..:...||:...::|:.||::::|.||..|..:::.||:..||||::.|||..:
Zfish   441 HAPRL--DTEGIELLLSFLRYESKKRISADESMKHSYFKSLGMRIHTLPESISIFTLKEVQLQRD 503

  Fly   517 PNRQN 521
            |..:|
Zfish   504 PGYRN 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	175/284 (62%)
cdk17	NP_001188286.1	STKc_PCTAIRE2	188..496	CDD:143377	189/314 (60%)