Protein Alignment Eip63E and cdk5

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001072776.1
• Gene: cdk5 / 780236
• XenbaseID: XB-GENE-1010261
• Length: 292
• Species: Xenopus tropicalis
• Alignment Length: 290
• Identity: 158/290 - (54%)
• Similarity: 202/290 - (69%)
• Gaps: 6/290 - (2%)

  Fly   203 EAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRL-QEEEGAPFTAIREASLLKELKHSNIVTL 266
            :.|.|||.:|||:|.||:|..::.|::.||||.:|| .::||.|.:|:||..|||||||.|||.|
 Frog     2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRL 66

  Fly   267 HDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQN 331
            ||::|:.:.||.||||.:.||.:|.:...|.||...|:.|::|||:||.:||.|.|||||:||||
 Frog    67 HDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLGFCHSRNVLHRDLKPQN 131

  Fly   332 LLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMV 396
            |||:..|||||||||||||..:|...||.|||||||||||||.|:..||||:|||..||||.|:.
 Frog   132 LLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELA 196

  Fly   397 -TGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDII 460
             .|.|.||| .|..|||.:||:|||||||:.||.:|..|.|||:.: :.....|.:..|:|.  .
 Frog   197 NAGRPLFPG-NDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPM-YPATMSLVNVVPKLN--A 257

  Fly   461 EGETIANGFLQLNPEQRLGADDALQHPYFA 490
            .|..:....|:.||.||:.||:||||||||
 Frog   258 TGRDLLQNLLKCNPVQRICADEALQHPYFA 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	155/286 (54%)
cdk5	NP_001072776.1	STKc_CDK5	3..286	CDD:143344	155/286 (54%)