Protein Alignment Eip63E and cdk5

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_571794.1
• Gene: cdk5 / 65234
• ZFINID: ZDB-GENE-010131-2
• Length: 292
• Species: Danio rerio
• Alignment Length: 290
• Identity: 155/290 - (53%)
• Similarity: 201/290 - (69%)
• Gaps: 6/290 - (2%)

  Fly   203 EAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRL-QEEEGAPFTAIREASLLKELKHSNIVTL 266
            :.|.|||.:|||:|.||:|..::.|::.||||.:|| .::||.|.:|:||..|||||||.|||.|
Zfish     2 QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRL 66

  Fly   267 HDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQN 331
            ||::|:.:.||.||||.:.||.:|.:...|.||...|:.|::|||:||::||.|.|||||:||||
Zfish    67 HDVLHSDKKLTLVFEYCDQDLKKYFDSCNGDLDPEIVKSFMYQLLKGLAFCHSRNVLHRDLKPQN 131

  Fly   332 LLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMV 396
            |||:..|||||||||||||..:|...||.|||||||||||||.|:..||||:|||..||||.|:.
Zfish   132 LLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELA 196

  Fly   397 -TGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDII 460
             .|.|.||| .|..|||.:||:|||||||:.|..:...|.|||:.: :.....|.:..|:|..
Zfish   197 NAGRPLFPG-NDVDDQLKRIFRLLGTPTEEQWQTMNKLPDYKPYPM-YPATTSLVNVVPKLSS-- 257

  Fly   461 EGETIANGFLQLNPEQRLGADDALQHPYFA 490
            .|..:....|:.||.||:.|::||||||||
Zfish   258 TGRDLLQNLLKCNPVQRISAEEALQHPYFA 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	152/286 (53%)
cdk5	NP_571794.1	STKc_CDK5	3..286	CDD:143344	152/286 (53%)