Protein Alignment Eip63E and Cdk4

DIOPT Version :9

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001286493.1
• Gene: Cdk4 / 36854
• FlyBaseID: FBgn0016131
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 125/337 - (37%)
• Similarity: 177/337 - (52%)
• Gaps: 48/337 - (14%)

  Fly   178 LNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQ-EE 241
            |.:|:....:|    ||...||..||    |..:|||:|.|||:....:|...||||::|:. .|
  Fly     7 LKRQKMSQAKK----FGDGDPFNYQE----LNIIGEGAYGTVYRARDVITGNIVALKKVRISLNE 63

  Fly   242 EGAPFTAIREASLLKEL---KHSNIVTLHDIVHTRE-----TLTFVFEYVNTDLSQYMEKHP-GG 297
            .|.|.:.:||.||||:|   .|:|||.|:::....|     .:..|||:|..|||..:::.| .|
  Fly    64 NGVPMSTLREISLLKQLNASNHANIVKLYEVCQFLERDGQLLILLVFEHVEQDLSDLIDRLPKSG 128

  Fly   298 LDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHE- 361
            :....::....:||.|:.:.|..|::|||:||||||:|..|.||:||||||:       ||..|
  Fly   129 MSPPTIQRLSRELLTGVDFLHSHRIIHRDLKPQNLLVSSQGHLKIADFGLAK-------TYGSEM 186

  Fly   362 -----VVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGT 421
                 |||||||.|:||| :..|::::|:|...||..||......|||..:. :|||:||:|.|.
  Fly   187 KLTSVVVTLWYRAPEVLL-AQPYNSTVDIWSAACIIFEMFNRRALFPGTSEK-NQLDRIFELTGR 249

  Fly   422 PTEDTWP-----GVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGAD 481
            |||..||     .:.|||...|.     ||:....:..:..|     .:.|..|..:...|..|.
  Fly   250 PTEQQWPQTISVALEHFPQRHPK-----RPKDFCPHLCKYAD-----DLLNKMLSYDLHLRPSAL 304

  Fly   482 DALQHPYFAQLP 493
            ..|:|.||.|.|
  Fly   305 ACLEHDYFQQEP 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	PLN00009	203..492	CDD:177649	115/309 (37%)
		STKc_PCTAIRE_like	204..489	CDD:270835	112/305 (37%)
Cdk4	NP_001286493.1	STKc_CDK4_6_like	26..312	CDD:270831	114/308 (37%)
		S_TKc	26..312	CDD:214567	114/308 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840