Protein Alignment Eip63E and Cdk17

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_006513689.1
• Gene: Cdk17 / 237459
• MGIID: 97517
• Length: 539
• Species: Mus musculus
• Alignment Length: 538
• Identity: 237/538 - (44%)
• Similarity: 315/538 - (58%)
• Gaps: 79/538 - (14%)

  Fly    30 LQKLKKRLSHSF-GRLTISR-----------------------EDGDESTHH--HHHHHHHRGGH 68
            ::|.|:|||.:. |..||..                       ::|...|.|  |...|.:.|..
Mouse    17 MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEESSSKDNEPIVKNGRPPTSHSVHSFLHQYTGSF 81

  Fly    69 ------------GGHHNHGNKVPYNGYNSEEYLDRLEPNGNIPADKTNCRYGAQESAKNDNNKPQ 121
                        ||.......:|.||    ..||.:..|..:.:|        .||.:.......
Mouse    82 KKPPLRRPHSVIGGSLGSFMAMPRNG----SRLDIVHENLKMGSD--------GESDQASGTSSD 134

  Fly   122 DWRSTDSTDHHDRVQRQLSVSSDSKLLD--EDIR------EEMKYHSHVVMRPKKPPRPKSEVFL 178
            :.:|.......:|:.|::|:...:|.|.  .|||      |:::..|        ||      |.
Mouse   135 EVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQISS--------PP------FD 185

  Fly   179 NKQETHPRRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEG 243
            .......||...|..|    |||.|.|:|||.||||:|||||||.||||...||||||||:.|||
Mouse   186 QPMSRRSRRASLSEIG----FGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEG 246

  Fly   244 APFTAIREASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLF 308
            ||.|||||.||||:|||:|||||||||||.::||.||||::.||.|||:.....:...||:|||:
Mouse   247 APCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLY 311

  Fly   309 QLLRGLSYCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVL 373
            |:||||:|||:|:|||||:|||||||::.|||||||||||||||||:.|||:|||||||||||||
Mouse   312 QILRGLAYCHRRKVLHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL 376

  Fly   374 LGSTEYSTSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKP 438
            |||:||||.:|||||||||.||.:|.|.||| ....|:|..||:|||||:::|||||:....:|.
Mouse   377 LGSSEYSTQIDMWGVGCIFFEMASGRPLFPG-STVEDELHLIFRLLGTPSQETWPGVSSNDEFKN 440

  Fly   439 HKLGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDET 503
            :....|:|:.|.::.|||..  ||..:...|||...::|:.|::|::|.||..|..:::.||:..
Mouse   441 YNFPKYKPQPLINHAPRLDS--EGIELITKFLQYESKKRVPAEEAMKHVYFRSLGPRIHALPESV 503

  Fly   504 SIFTVEGVQLYTEPNRQN 521
            |||:::.:||..:|..:|
Mouse   504 SIFSLKEIQLQKDPGFRN 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	178/284 (63%)
Cdk17	XP_006513689.1	STKc_PCTAIRE2	201..509	CDD:143377	191/314 (61%)