Protein Alignment Eip63E and Cdk16

DIOPT Version :9

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_035179.1
• Gene: Cdk16 / 18555
• MGIID: 97516
• Length: 496
• Species: Mus musculus
• Alignment Length: 528
• Identity: 231/528 - (43%)
• Similarity: 302/528 - (57%)
• Gaps: 95/528 - (17%)

  Fly    30 LQKLKKRLSHSF-GRLTISREDG-------DESTHHHHHHHHHRGGHGGHHNHGNKVPYNGYNSE 86
            ::|:|::||.:. |...|.:.:|       |||            |.||..:.|.
Mouse     4 MKKIKRQLSMTLRGGRGIDKTNGVPEQIGLDES------------GGGGGSDLGE---------- 46

  Fly    87 EYLDRLEPNGNIPADKTNCR---YGAQESAKNDNNKPQDWRSTDSTDHHDRVQRQLSVSSDSKLL 148
                  .|....|.:..:.|   ..|.|....|.....|..|..::          :.|||.  :
Mouse    47 ------APTRIAPGELRSVRGPLSSAPEIVHEDMKMGSDGESDQAS----------ATSSDE--V 93

  Fly   149 DEDIREEMKYHSHVVMRPKKPPRPKSEVFLNKQETHP---------------------------- 185
            ...:|..|:.|         |||..|...:||:.:.|
Mouse    94 QSPVRVRMRNH---------PPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRL 149

  Fly   186 RRKRFSAFGGDSPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIR 250
            ||...|..|    |||.|.|:||:.||||:|||||||.||||...||||||||:.|||||.||||
Mouse   150 RRVSLSEIG----FGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIR 210

  Fly   251 EASLLKELKHSNIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLS 315
            |.||||:|||:||||||||:||.::||.||||::.||.||::.....::..||:||||||||||:
Mouse   211 EVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLA 275

  Fly   316 YCHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYS 380
            |||:::|||||:|||||||::.|||||||||||||||:|:.|||:|||||||||||:|||||:||
Mouse   276 YCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340

  Fly   381 TSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYR 445
            |.:|||||||||.||.||.|.||| ....:||..||::||||||:||||:.....::.:....||
Mouse   341 TQIDMWGVGCIFYEMATGRPLFPG-STVEEQLHFIFRILGTPTEETWPGILSNEEFRTYNYPKYR 404

  Fly   446 PRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEG 510
            ...|..:.|||..  :|..:....||.....|:.|:||.:||:|..|.:::::|||.||||.::.
Mouse   405 AEALLSHAPRLDS--DGADLLTKLLQFEGRNRISAEDARKHPFFLSLGERIHKLPDTTSIFALKE 467

  Fly   511 VQLYTEPN 518
            |||..|.|
Mouse   468 VQLQKEAN 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	PLN00009	203..492	CDD:177649	176/288 (61%)
		STKc_PCTAIRE_like	204..489	CDD:270835	174/284 (61%)
Cdk16	NP_035179.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95		25/130 (19%)
		STKc_PCTAIRE1	162..458	CDD:270854	178/298 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3201
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850