Protein Alignment Eip63E and cdk-14

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_490783.3
• Gene: cdk-14 / 171672
• WormBaseID: WBGene00022519
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 218/514 - (42%)
• Similarity: 283/514 - (55%)
• Gaps: 89/514 - (17%)

  Fly    21 TMREKKGGALQKLKKRLSHSFGRLT---ISREDGDESTHHHHHHH----HHRGGHGGHHNHGNKV 78
            |:|..:    .|.||..::..|..|   ||:...:|.|...|.:|    ....|.|....|.||
 Worm    77 TLRRSR----NKEKKYKNNGGGGSTKSPISKNGTNEMTQSWHSNHVNGASSGSGSGSTPEHHNK- 136

  Fly    79 PYNGYNSEEYLDRLEPNGNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDRVQRQLSVSS 143
                 |...:|.|                    .:::.:|.|.:..||            :.::.
 Worm   137 -----NIFSFLSR--------------------QSRSRSNNPSETMST------------VPLNK 164

  Fly   144 DSKLLDEDIREEMKYHSHVVMRPKKPPRPKSEVFLNKQETHPRRKRFSAFGGD------------ 196
            :|                    |..||.|.|....:  .||.||:|..:...|
 Worm   165 NS--------------------PSMPPPPSSNTVAD--FTHLRRRRPRSAHYDPNTITLPAKEEV 207

  Fly   197 SPFGKQEAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHS 261
            :|....:.|.:::.|||||||||||..|||....||||||:||.:||.|||||||||||:.|:|:
 Worm   208 TPQDVNDLYKRIDKLGEGSYATVYKCESKLDGSIVALKEIKLQFQEGLPFTAIREASLLRNLRHA 272

  Fly   262 NIVTLHDIVHTRETLTFVFEYVNTDLSQYMEKHPGGLDHRNVRLFLFQLLRGLSYCHKRRVLHRD 326
            |||:||||.:....|||||||:..|||:|:|::..|||..:::|.||||||||.:||::::||||
 Worm   273 NIVSLHDIFYQHHQLTFVFEYMKMDLSKYLEQNVYGLDSIDIKLLLFQLLRGLDFCHRKKILHRD 337

  Fly   327 VKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCI 391
            :||||||:.:.|.||||||||||||||||.|||||||||||||||||:|||:|||||||||||||
 Worm   338 LKPQNLLLDEDGVLKLADFGLARAKSVPSRTYSHEVVTLWYRPPDVLMGSTDYSTSLDMWGVGCI 402

  Fly   392 FVEMVTGMPTFPGIRD-----TYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGH 451
            |.|:.||...|||.:|     |.||||.||.:.|||.|..||.|...|||.|.....||......
 Worm   403 FAEICTGAALFPGSKDSHYPGTKDQLDMIFSIRGTPDEKKWPEVKTLPGYTPELFPRYRELSFIA 467

  Fly   452 NFPRLYDIIE-GETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVE 509
            ..|....|:: |:.:....|||.||.|:.|..|:.|||||..|::::.|....|||.::
 Worm   468 VNPMFTKILKTGQELLGMLLQLRPESRVSAASAMLHPYFASFPREVHLLAPSQSIFRLK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	172/290 (59%)
cdk-14	NP_490783.3	Protein Kinases, catalytic domain	216..506	CDD:473864	172/289 (60%)