Protein Alignment Eip63E and Cdk4

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_315841.3
• Gene: Cdk4 / 1276486
• VectorBaseID: AGAMI1_007178
• Length: 302
• Species: Anopheles gambiae
• Alignment Length: 313
• Identity: 116/313 - (37%)
• Similarity: 169/313 - (53%)
• Gaps: 43/313 - (13%)

  Fly   205 YVKLEPLGEGSYATVYKGFS-KLTYQRVALKEIRLQ-EEEGAPFTAIREASLLKELK---HSNIV 264
            |.:|..:|.|:|.|||:... |.....||||::|:. .|:|.|.:.:||..:||:|.   |.|:|
Mosquito     6 YEELGVIGTGAYGTVYRARDLKNAGTIVALKKVRVALTEDGVPMSTLREIFMLKQLDTFGHPNVV 70

  Fly   265 TLHDIVH----TRE---TLTFVFEYVNTDLSQYMEK-HPGGLDHRNVRLFLFQLLRGLSYCHKRR 321
            .|.|:..    .||   .|..|||:::.||.:|::: .|.|:....::....::|.|:.:.|..|
Mosquito    71 KLLDVCQGQRLEREGQLVLFLVFEHLDHDLDEYIKRLPPKGMPPATIQRLSREMLTGIDFLHSHR 135

  Fly   322 VLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHE------VVTLWYRPPDVLLGSTEYS 380
            ::|||:||||||||..|.|||||||||:       ||..|      |||||||.|:||||.. |:
Mosquito   136 IIHRDLKPQNLLISSDGHLKLADFGLAK-------TYDFEMKLTTVVVTLWYRAPEVLLGEA-YN 192

  Fly   381 TSLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWP-GVT----HFPGYKPHK 440
            :|:|:|..|||..||......|||..:. :||::||:|.|.|:|..|| |::    :|...:..:
Mosquito   193 SSVDIWSAGCIIAEMFQRQALFPGTAEG-NQLERIFELTGRPSEAQWPRGISIVRENFRSTQRRE 256

  Fly   441 LGFYRPRKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLP 493
                 ||:.   .|:|.|  ....:....|..:..:|..|...|.|.||.|.|
Mosquito   257 -----PREF---CPKLCD--NANDLLKSMLAFSRHERPSARQCLNHAYFKQEP 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	112/307 (36%)
Cdk4	XP_315841.3	STKc_CDK4_6_like	6..295	CDD:270831	112/307 (36%)