Protein Alignment Eip63E and Cdk11b

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_031687.2
• Gene: Cdk11b / 12537
• MGIID: 88353
• Length: 784
• Species: Mus musculus
• Alignment Length: 601
• Identity: 169/601 - (28%)
• Similarity: 254/601 - (42%)
• Gaps: 135/601 - (22%)

  Fly    23 REKKGGALQKLKKRLSHSFGRLTISREDGDESTHHHHHHHHHR-----GGHGGHHNHG------- 75
            ||:|....||.::.......|....|::.:.......||...|     .|..||.:..
Mouse   177 RERKLREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREEYSDKGKVGHWSRSPLRPPRE 241

  Fly    76 ------NKVPYNGYNSEE---------YLDRLEPNGNIPADKTNCRYGAQESAKNDNNKPQDWRS 125
                  |:.|......||         ..|......:..:.......|::|..:.:..:.::..|
Mouse   242 RFEMGDNRKPVKEEKVEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEEGS 306

  Fly   126 TDSTDHHDRVQ-------------RQLSVSSDSKLLDEDIR--EEMKYHSHVVMRPKKPPRPKSE 175
            |......:..:             .:.|..|..::.||::.  |:.:..:|:::.|:
Mouse   307 TSEESEEEEEEEEEEEEEETGSNSEEASEQSAEEVSDEEMSEDEDRENENHILVVPE-------- 363

  Fly   176 VFLNKQETHPRRKRFSAFGGDSPFGKQEA--------------YVKLEP---------------- 210
                        .||....|||..|::|.              ||...|
Mouse   364 ------------SRFDRDSGDSEEGEEEVGEGTPQSSAPTEGDYVPDSPALSPIELKQELPKYLP 416

  Fly   211 ----------------LGEGSYATVYKGFSKLTYQRVALKEIRLQ-EEEGAPFTAIREASLLKEL 258
                            :.||:|..||:...|.|.:.||||.:::: |:||.|.|::||.:.:.:.
Mouse   417 ALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA 481

  Fly   259 KHSNIVTLHDIV--HTRETLTFVFEYVNTDLSQYMEKH-----PGGLDHRNVRLFLFQLLRGLSY 316
            :|.||||:.:||  ...:.:..|..||..||...||..     ||     .|:..:.|||.|:.:
Mouse   482 QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPG-----EVKTLMIQLLSGVKH 541

  Fly   317 CHKRRVLHRDVKPQNLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYST 381
            .|...:||||:|..|||:|..|.||:.||||||....|...|:..|||||||.|::|||:.||||
Mouse   542 LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYST 606

  Fly   382 SLDMWGVGCIFVEMVTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRP 446
            ::|||.|||||.|::|..|.|||..| .||::||||.||||:|..|||....|..|......|..
Mouse   607 AVDMWSVGCIFGELLTQKPLFPGKSD-IDQINKIFKDLGTPSEKIWPGYNDLPAVKKMTFSEYPY 670

  Fly   447 RKLGHNFPRLYDIIEGETIANGFLQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEGV 511
            ..|...|..|.. .:|..:.|.||...|.:|:.|:|.|:|.||.:.|     ||.:.|:|.
Mouse   671 NNLRKRFGALLS-DQGFDLMNKFLTYYPGRRINAEDGLKHEYFRETP-----LPIDPSMFP---- 725

  Fly   512 QLYTEPNRQNKXKLKQ 527
               |.|.:..:.::|:
Mouse   726 ---TWPAKSEQQRVKR 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	123/338 (36%)
Cdk11b	NP_031687.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..401		38/243 (16%)
		STKc_CDC2L1	421..712	CDD:173741	120/297 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	722..784		5/24 (21%)