Protein Alignment Eip63E and CDK3

DIOPT Version :9

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001249.1
• Gene: CDK3 / 1018
• HGNCID: 1772
• Length: 305
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 156/300 - (52%)
• Similarity: 202/300 - (67%)
• Gaps: 26/300 - (8%)

  Fly   203 EAYVKLEPLGEGSYATVYKGFSKLTYQRVALKEIRLQ-EEEGAPFTAIREASLLKELKHSNIVTL 266
            :.:.|:|.:|||:|..|||..::.|.|.||||:|||. |.||.|.|||||.||||||||.|||.|
Human     2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRL 66

  Fly   267 HDIVHTRETLTFVFEYVNTDLSQYMEKHPGG-LDHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQ 330
            .|:||....|..|||:::.||.:||:..||. |....::.:|||||:|:|:||..||:|||:|||
Human    67 LDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQ 131

  Fly   331 NLLISDCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEM 395
            ||||::.|.:||||||||||..||..||:|||||||||.|::||||..|:|::|:|.:||||.||
Human   132 NLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEM 196

  Fly   396 VTGMPTFPGIRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPR----- 455
            ||....|||..: .|||.:||::||||:||||||||..|.||             .:||:
Human   197 VTRKALFPGDSE-IDQLFRIFRMLGTPSEDTWPGVTQLPDYK-------------GSFPKWTRKG 247

  Fly   456 LYDII-----EGETIANGFLQLNPEQRLGADDALQHPYFA 490
            |.:|:     ||..:....||.:|.||:.|..||.||||:
Human   248 LEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	PLN00009	203..492	CDD:177649	156/299 (52%)
		STKc_PCTAIRE_like	204..489	CDD:270835	154/296 (52%)
CDK3	NP_001249.1	PLN00009	1..293	CDD:177649	156/299 (52%)
		STKc_CDK2_3	3..286	CDD:270844	154/296 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820