Protein Alignment Eip63E and CDK2

DIOPT Version :10

• Sequence 1: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_011536034.1
• Gene: CDK2 / 1017
• HGNCID: 1771
• Length: 346
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 50/216 - (23%)
• Similarity: 85/216 - (39%)
• Gaps: 55/216 - (25%)

  Fly   274 GKDFS-------EKRYDGTIIG-----VNDMSPHWKDSEWRSLKVQWDELSPFLRPNQVSPWDIE 326
            ||:.|       |.:|...||.     |.::|.  |.||..:.:....|:|   :..||...||
Human   251 GKEVSRLSDYEIESKYKDVIIANLQNEVAELSQ--KVSETTTSRQNEKEIS---QKCQVLDEDI- 309

  Fly   327 HLIPSSDISQSSLKKKKHWLQLNEIGATLSNLWTCQEIGQRSMNSPISVPEFSYPNAIEDSKFLS 391
                  |..|..::..|.  |::.:....|.: .||.:.:|  ||.|:..:....|...|:...|
Human   310 ------DAKQKEIQSLKS--QISALQKGYSKV-LCQTLSER--NSEITSLKNEGENLKRDNAITS 363

  Fly   392 GLL--LNHSLLAIPNENYNSDQMIQPRKEDIT------------TEATTS-CLLFGVDLTKVSKS 441
            |::  |...:||       .|:.:|..||:::            .||..| |.:...:|    |.
Human   364 GMVSSLQKDILA-------KDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEEL----KQ 417

  Fly   442 KDSICPIESCKKSEISKLKNQ 462
            :|:...:...::.|:...|.|
Human   418 EDAHRELREAQEKELKLCKTQ 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip63E	NP_001261373.1	STKc_PCTAIRE_like	204..489	CDD:270835	50/216 (23%)
CDK2	XP_011536034.1	STKc_CDK2_3	3..334	CDD:270844	23/97 (24%)