DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42324 and BEGAIN

DIOPT Version :9

Sequence 1:	NP_647819.3	Gene:	CG42324 / 38430	FlyBaseID:	FBgn0259224	Length:	1037	Species:	Drosophila melanogaster
Sequence 2:	NP_001372014.1	Gene:	BEGAIN / 57596	HGNCID:	24163	Length:	642	Species:	Homo sapiens

Alignment Length:	215	Identity:	61/215 - (28%)
Similarity:	98/215 - (45%)	Gaps:	24/215 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PAIAATPLATSAPAAAEIEQLQQALIEKQTQL-----YALESACLRETE-------RQVEL---E 82
            |.:....||.|:|:..:     .||.|::.:|     |........|||       .::||   :
Human    37 PRVLQGRLARSSPSIWD-----SALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQ 96

  Fly    83 DSVIAWQDKYDRLYESHKRVQKVNQSLEDKMLKLVDRNAGERAQLTSDVATLSVRLAQANFNIAK 147
            :.:....:|..|:..::..:|::||.||||:.::......|:..|:.::..|:..|.:|...|.|
Human    97 EELEKVTEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRALSHEIVALNSHLLEAKVTIDK 161

  Fly   148 LQREIERYKADISLAIQLLQCKPDSFVSQKVSSLPIDIQSKVSAYMRLETNSHSDSECSNS-GVG 211
            |..:.|.|:.|.:||.|||||........|||.||.|.|.:||.:|.....|.....|..: ...
Human   162 LSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQERVSLHMEKHGCSLPSPLCHPAYADS 226

  Fly   212 VATTASYKVLPASDSPPPSA 231
            |.|....|||   :.|.|::
Human   227 VPTCVIAKVL---EKPDPAS 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42324	NP_647819.3	DUF4200	49..156	CDD:290574	28/121 (23%)
BEGAIN	NP_001372014.1	Smc	<55..>180	CDD:224117	33/124 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004208
OrthoInspector	1	1.000	-	-		otm42209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR28664
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5758
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.130