DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and CLN1

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_013926.1	Gene:	CLN1 / 855239	SGDID:	S000004812	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	198	Identity:	41/198 - (20%)
Similarity:	75/198 - (37%)	Gaps:	37/198 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VAAEQNIFVVDRKLKKTCPQADVERLAKTHWLTDYARDIFLTMREQELSRRP---LFYLSPQLN- 65
            |.|:|..:.::        .::.|.|.....:.:|..:|...:..|....:|   |....|::|
Yeast    12 VTAKQTYYPIE--------LSNAELLTHYETIQEYHEEISQNVLVQSSKTKPDIKLIDQQPEMNP 68

  Fly    66 --ERRRMLQLLKLATSAHKLSRCALHLAVYYMDRFVDYYKIRPDKLLLVAITCLHIAAQI----- 123
              .|..::..|...:...::|......||.:.||:.....:..|:..||..|||.:||:.
Yeast    69 HQTREAIVTFLYQLSVMTRVSNGIFFHAVRFYDRYCSKRVVLKDQAKLVVGTCLWLAAKTWGGCN 133

  Fly   124 ----------------ENTDAFIPRYSEMNRLV--KNAYTAFEYKAVERKILCFLNFELIRPTTA 170
                            .|..|.|||.||:....  .:.:....:..:||.||..||:::..|...
Yeast   134 HIINNVSIPTGGRFYGPNPRARIPRLSELVHYCGGSDLFDESMFIQMERHILDTLNWDVYEPMIN 198

  Fly   171 SFV 173
            .::
Yeast   199 DYI 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	34/150 (23%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044
CLN1	NP_013926.1	COG5024	31..539	CDD:227357	36/171 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000