DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and CCNP

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	XP_006723458.2	Gene:	CCNP / 79935	HGNCID:	25805	Length:	397	Species:	Homo sapiens

Alignment Length:	161	Identity:	42/161 - (26%)
Similarity:	73/161 - (45%)	Gaps:	22/161 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 PQADVERLAKTHWL------------TDYARDIFLTMREQELSR-RPLFYLSPQLNERRRMLQLL 74
            |.....|||:...|            .:||.|||   .|..:.| .||..|...:....|.| ::
Human   120 PTVSPRRLARPPGLEEALSALGLQGEREYAGDIF---AEVMVCRVLPLRALPRAVTPEMRAL-VV 180

  Fly    75 KLATSAHK---LSRCALHLAVYYMDRFVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEM 136
            ......|:   |:...|:|||:.:|.::...::|..:|.|:.:.||.:|.::|  :..:|..:.:
Human   181 DWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVACKME--ECVLPEPAFL 243

  Fly   137 NRLVKNAYTAFEYKAVERKILCFLNFELIRP 167
            ..|..::::..|....||:||..|:|.|..|
Human   244 CLLSADSFSRAELLRAERRILSRLDFRLHHP 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	33/125 (26%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044
CCNP	XP_006723458.2	Cyclin_N	171..271	CDD:278560	25/102 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810