DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and ccne1

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_571070.1	Gene:	ccne1 / 30188	ZFINID:	ZDB-GENE-980526-168	Length:	410	Species:	Danio rerio

Alignment Length:	376	Identity:	77/376 - (20%)
Similarity:	149/376 - (39%)	Gaps:	92/376 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEQKVA---------AEQNIFVVDRK---LKKTCPQADVERLAKTHWLTDYARDIFLTMREQELS 53
            :|:.||         |.::||:...:   |...|..:..|     .|.....:|.......:.:.
Zfish    78 VEEPVAFGSVGFTQYASESIFITPTRSTPLPALCWASKDE-----VWNNLLGKDKLYLRDTRVME 137

  Fly    54 RRPLFYLSPQLNERRRMLQLLKLATSAHKLSRCALHLAVYYMDRFV-DYYKIRPDKLLLVAITCL 117
            |.|  .|.|::  |..:|..|......:||.|...:|...|.|||: ....:....|.|:.|:||
Zfish   138 RHP--NLQPKM--RAILLDWLMEVCEVYKLHRETFYLGQDYFDRFMATQENVLKTTLQLIGISCL 198

  Fly   118 HIAAQIENTDAFIPRYSEMNRLVKNAYTAFEYKAVERKILCFLNFELIRPTTASFVELFACSFLT 182
            .|||::|  :.:.|:..:...:...|.|..:..::|..|:..||:.|...|..:::.:    ::.
Zfish   199 FIAAKME--EIYPPKVHQFAYVTDGACTEDDILSMEIIIMKELNWSLSPLTPVAWLNI----YMQ 257

  Fly   183 RSDFKNYIEMLD-EYERNHHTQPYQRYISFEEMLSILAQLLLRMADYTLYISRFANDLPSLLAAA 246
            .:..|...|:|. :|       |...::...|:|. |..|.:|..:::.          |||||:
Zfish   258 MAYLKETAEVLTAQY-------PQATFVQIAELLD-LCILDVRSLEFSY----------SLLAAS 304

  Fly   247 C------IAAVRQVSGVR--------RWSEYLVGLTSYTEANVEPY-MNVLTDYYYYHVIQTDYG 296
            .      :..|.:|||::        ||              :.|: |::           .:.|
Zfish   305 ALFHFSSLELVIKVSGLKWCDLEECVRW--------------MVPFAMSI-----------REAG 344

  Fly   297 SPSVQTNQSLASPDSGFEESFTENTNLVVSDEVVTVETYNIITVQLQDPSP 347
            |.:::|.:.:|:.|     .....|::...:.:..|.:|.::.::....||
Zfish   345 SSALKTFKGIAADD-----MHNIQTHVPYLEWLGKVHSYQLVDIESSQRSP 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	32/122 (26%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	13/75 (17%)
ccne1	NP_571070.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		Cyclin_N	117..244	CDD:278560	34/137 (25%)
		Cyclin_C	247..368	CDD:281044	30/172 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	387..410		2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920