DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and Ccno

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_001074531.1	Gene:	Ccno / 218630	MGIID:	2145534	Length:	352	Species:	Mus musculus

Alignment Length:	218	Identity:	56/218 - (25%)
Similarity:	88/218 - (40%)	Gaps:	34/218 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DYARDIFLTMREQELSRRPLFYLS--PQLNERRRMLQLLKLATSAHK---LSRCALHLAVYYMDR 97
            :|.:..:...:.||....|...|:  ||:....| .:||......|:   ||..:|.|.|..:||
Mouse   102 EYGQSCYDFRKAQENLFHPRESLARQPQVTAESR-CKLLSWLLQVHRQFGLSFESLCLTVNTLDR 165

  Fly    98 FVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVKNAYTAFEYKAVERKILCFLNF 162
            |:....:..|...|:.:|||.||.  :..:...||..::..|...|::..:...:|..:|..|:|
Mouse   166 FLLTTPVAADCFQLLGVTCLLIAC--KQVEVHPPRLKQLLALCGGAFSRQQLCNLECIVLHKLHF 228

  Fly   163 ELIRPTTASFVELFACSFLTRSDFKNYIEMLDEYERNHHTQPYQRYISFEEMLSILAQLLLR-MA 226
            .|..||...|:|                         |.||........|...::.||.|.| :|
Mouse   229 SLGAPTINFFLE-------------------------HFTQWRMEAGQAEVTEALEAQTLARGVA 268

  Fly   227 DYTLYISRFANDLPSLLAAACIA 249
            :.:|....|....|||:|..|:|
Mouse   269 ELSLTDYAFTTYTPSLMAICCLA 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	33/126 (26%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	9/25 (36%)
Ccno	NP_001074531.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40
		Cyclin_N	108..231	CDD:278560	33/125 (26%)
		Cyclin_C	233..>301	CDD:281044	21/84 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900