DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycJ and ccna2

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_694481.1	Gene:	ccna2 / 192295	ZFINID:	ZDB-GENE-020418-1	Length:	428	Species:	Danio rerio

Alignment Length:	264	Identity:	71/264 - (26%)
Similarity:	110/264 - (41%)	Gaps:	38/264 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ERLAKTHWLTDYARDIFLTMREQELSRRP-LFYLSPQ---LNERRRML-QLLKLATSAHKLSRCA 87
            ||....:.::|||.:|...:||.|:..:| ..|:..|   .|..|.:| ..|......:||....
Zfish   163 ERPTNVNEVSDYAAEIHTHLREMEVKSKPKAGYMRKQPDITNSMRAILVDWLVEVGEEYKLQNET 227

  Fly    88 LHLAVYYMDRFVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVKNAYTAFEYKAV 152
            |:|||.|:|||:....:...||.||....:.:|::.|  :.:.|..:|...:..:.||..:...:
Zfish   228 LYLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFE--EIYPPEVAEFVYITDDTYTKKQVLRM 290

  Fly   153 ERKILCFLNFELIRPTTASFVELFACSFLTRSDFKNYIEMLDEYERNHHTQPYQRYISFEEMLSI 217
            |..:|..|:|:|..||...|:..:   ||                   | ||....:  |.:...
Zfish   291 EHLVLTVLSFDLAAPTINQFLTQY---FL-------------------H-QPVSSKV--ESLSMF 330

  Fly   218 LAQLLLRMADYTLYISRFANDLPSLLAAACIAAVRQVSGVRRWSEYLVGLTSYTEANVEPYMNVL 282
            |.:|.|...|      .|...|||.:|||.............||:.||.||.|:..::.|.:..|
Zfish   331 LGELSLIDCD------PFLKYLPSQMAAAAFILANHTLASGSWSKSLVDLTGYSLEDLLPCVQDL 389

  Fly   283 TDYY 286
            ...|
Zfish   390 HQTY 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	35/126 (28%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	17/60 (28%)
ccna2	NP_694481.1	Cyclin_N2	33..157	CDD:293109
		Cyclin_N	177..303	CDD:278560	35/127 (28%)
		Cyclin_C	305..422	CDD:281044	30/120 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820