DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycJ and Ccne2

DIOPT Version :9

Sequence 1:	NP_523903.1	Gene:	CycJ / 38428	FlyBaseID:	FBgn0010317	Length:	386	Species:	Drosophila melanogaster
Sequence 2:	NP_001032211.1	Gene:	Ccne2 / 12448	MGIID:	1329034	Length:	404	Species:	Mus musculus

Alignment Length:	291	Identity:	64/291 - (21%)
Similarity:	117/291 - (40%)	Gaps:	63/291 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 LSPQLNERRRMLQLLKLATSAHKLSRCALHLAVYYMDRFVDYYK-IRPDKLLLVAITCLHIAAQI 123
            |.||:  |..:|..|......:.|.|...:||..:.|||:...| :..:.|.|:.||.|.||:::
Mouse   137 LEPQM--RSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKL 199

  Fly   124 ENTDAFIPRYSEMNRLVKNAYTAFEYKAVERKILCFLNFELIRPTTASFVELFACSFLTRSDFKN 188
            |  :.:.|:..|...:...|.:..:...:|..||..|.:||...|..|::.|    ||.....|:
Mouse   200 E--EIYAPKLQEFAYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNL----FLQVDAVKD 258

  Fly   189 YIE-MLDEYERNHHTQPYQRYISFEEMLSILAQLLLRMADYTLYISRFANDLPSLLAAAC----- 247
            ..: :|.:|.:       :.:|...::|. |..|.:...::...|          ||||.
Mouse   259 VPKVLLPQYSQ-------ETFIQIAQLLD-LCILAIDSLEFQYRI----------LAAAALCHFT 305

  Fly   248 -IAAVRQVSGVRRWS------EYLVGLTSYTEA------------------NVEP---YMNVLTD 284
             |..|::.||: .|.      :::|...|..::                  |::.   |:.:|.:
Mouse   306 SIEVVKKASGL-EWDDISECVDWMVPFVSVVKSVSPVKLKTFKKIPMEDRHNIQTHTNYLALLNE 369

  Fly   285 YYYYHVIQTDYGSPSVQTNQSLASPDSGFEE 315
            ..|.::.:.. |..|...|..:.:|....|:
Mouse   370 VNYVNIYRKG-GQLSPVCNGGIMTPPKSTEK 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycJ	NP_523903.1	Cyclin_N	42..164	CDD:278560	29/104 (28%)
CycJ	NP_523903.1	Cyclin_C	<225..>286	CDD:281044	15/93 (16%)
Ccne2	NP_001032211.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41
		Cyclin_N	112..239	CDD:365896	30/105 (29%)
		Cyclin_C	241..361	CDD:367282	25/142 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820